Increasing Post‐Digestive Solubility of Curcumin Is the Most Successful Strategy to Improve its Oral Bioavailability: A Randomized Cross‐Over Trial in Healthy Adults and In Vitro Bioaccessibility Experiments

Scope Different mechanistic approaches to improve the low oral bioavailability of curcumin have been developed, but not yet directly compared in humans. Methods and Results In a randomized, double‐blind, cross‐over trial with 12 healthy adults, the 24 h pharmacokinetics of a single dose of 207 mg cu...

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