Development of thermosensitive and mucoadhesive gels of cabotegravir for enhanced permeation and retention profiles in vaginal tissue: A proof of concept study

[Display omitted] •Cabotegravir were formulated into thermosensitive and mucoadhesive vaginal gels.•The gels possessed desired thermosensitive and mucoadhesive properties.•The use of PEG 400 was able to increase the permeation and the localization in vaginal tissue in ex vivo studies.•The gels were...

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Veröffentlicht in:	International journal of pharmaceutics 2021-11, Vol.609, p.121182-121182, Article 121182
Hauptverfasser:	Enggi, Cindy Kristina, Isa, Hansel Tridatmojo, Sulistiawati, Sulistiawati, Ardika, Komang Agus Rai, Wijaya, Stevens, Asri, Rangga Meidianto, Mardikasari, Sandra Aulia, Donnelly, Ryan F., Permana, Andi Dian
Format:	Artikel
Sprache:	eng
Schlagworte:	Cabotegravir HIV Mucoadhesive Thermosensitive vaginal gel
Online-Zugang:	Volltext
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