Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation
Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level laser therapy. Male Wistar rats were divided into 5 groups: N...
Gespeichert in:
| Veröffentlicht in: | Journal of photochemistry and photobiology. B, Biology Biology, 2021-12, Vol.225, p.112332-112332, Article 112332 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 112332 |
|---|---|
| container_issue | |
| container_start_page | 112332 |
| container_title | Journal of photochemistry and photobiology. B, Biology |
| container_volume | 225 |
| creator | Mármora, Belkiss Câmara Brochado, Fernanda Thomé Schmidt, Tuany Rafaelli Santos, Lucas Gonçalves Araújo, Aurigena Antunes de Medeiros, Caroline Addison Carvalho Xavier de Ribeiro, Susana Barbosa Martins, Marco Antonio Trevizani Pilar, Emily Ferreira Salles Wagner, Vivian Petersen Martins, Manoela Domingues |
| description | Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level laser therapy. Male Wistar rats were divided into 5 groups: Negative control; Sham; 0.1 W laser (L0.1 W); DHPL Dual 1 W (DHPLD1 W); and DHPL Dual 2 W (DHPLD2 W). Rats were euthanized on days 3, 5, 10, 14 and 21. Clinical, morphological, PicroSirus, oxidative stress (MDA, SOD and GSH) and cytokines (IL-1β, IL-10 and TNF-α) analyses were performed. A faster clinical repair was observed in all laser groups at D10 and D14. DHPLD1 W exhibited lower inflammation and better reepithelization compared to other groups at D10. DHPL protocols modulated oxidative stress by decreasing MDA and increasing SOD and GSH. Collagen maturation was triggered by all protocols tested and L0.1 W modulated cytokines release (IL-1β and TNF-α) at D3. In conclusion, DHPL, especially DHPL1 W protocol, accelerated skin healing by triggering reepithelization and collagen maturation and modulating inflammation and oxidative stress.
•Defocused high-power diode laser (DHPL) is a promising therapy for wound healing•DHPL effect on skin repair had never been evaluated an animal model study•DHPL was as effective as low-level laser therapy in accelerating skin repair•DHPL triggered reepithelization and collagen maturation during skin repair•DHPL modulated inflammation and oxidative stress during skin repair |
| doi_str_mv | 10.1016/j.jphotobiol.2021.112332 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2582816041</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1011134421002116</els_id><sourcerecordid>2620965609</sourcerecordid><originalsourceid>FETCH-LOGICAL-c402t-a627321b3efcbf416b47b94e2aeb1be33ec7b2222c77986e39b87cd5700887723</originalsourceid><addsrcrecordid>eNqFkctu1DAUhiMEoqXwCsgSGzYZfEnsZAltuUiVKiGQ2Fm-nEwcnDjYDggehyfFwwxUYsPZ-Nfx9_vY_qsKEbwjmPAX025ax5CDdsHvKKZkRwhljN6rzkknWE15R-8XjQmpCWuas-pRShMu1XLxsDpjDW9ZT_vz6ucVDMFsCSwa3X6s1_ANIrIuWEBepaKVMeAhqgwJpc9uQRFW5SIqSqF5i24BNBfcozzGsO1H9P766vYTSrlYDjubV9mFQi-2eGF1eQTvftw1TfBe7WFBFtaQ3O9-ym4-GR9XDwblEzw5rRfVx9fXHy7f1je3b95dvrypTYNprhWnglGiGQxGDw3huhG6b4Aq0EQDY2CEpqWMEH3HgfW6E8a2AuOuE4Kyi-r58dw1hi8bpCxnl8rbvVogbEnStqMd4bghBX32DzqFLS7ldpJyinvectwXqjtSJoaUIgxyjW5W8bskWB5ylJO8y1EecpTHHIv16WnApmewf41_givAqyMA5Ue-OogyGQeLAesimCxtcP-f8guUKbbc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2620965609</pqid></control><display><type>article</type><title>Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Mármora, Belkiss Câmara ; Brochado, Fernanda Thomé ; Schmidt, Tuany Rafaelli ; Santos, Lucas Gonçalves ; Araújo, Aurigena Antunes de ; Medeiros, Caroline Addison Carvalho Xavier de ; Ribeiro, Susana Barbosa ; Martins, Marco Antonio Trevizani ; Pilar, Emily Ferreira Salles ; Wagner, Vivian Petersen ; Martins, Manoela Domingues</creator><creatorcontrib>Mármora, Belkiss Câmara ; Brochado, Fernanda Thomé ; Schmidt, Tuany Rafaelli ; Santos, Lucas Gonçalves ; Araújo, Aurigena Antunes de ; Medeiros, Caroline Addison Carvalho Xavier de ; Ribeiro, Susana Barbosa ; Martins, Marco Antonio Trevizani ; Pilar, Emily Ferreira Salles ; Wagner, Vivian Petersen ; Martins, Manoela Domingues</creatorcontrib><description>Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level laser therapy. Male Wistar rats were divided into 5 groups: Negative control; Sham; 0.1 W laser (L0.1 W); DHPL Dual 1 W (DHPLD1 W); and DHPL Dual 2 W (DHPLD2 W). Rats were euthanized on days 3, 5, 10, 14 and 21. Clinical, morphological, PicroSirus, oxidative stress (MDA, SOD and GSH) and cytokines (IL-1β, IL-10 and TNF-α) analyses were performed. A faster clinical repair was observed in all laser groups at D10 and D14. DHPLD1 W exhibited lower inflammation and better reepithelization compared to other groups at D10. DHPL protocols modulated oxidative stress by decreasing MDA and increasing SOD and GSH. Collagen maturation was triggered by all protocols tested and L0.1 W modulated cytokines release (IL-1β and TNF-α) at D3. In conclusion, DHPL, especially DHPL1 W protocol, accelerated skin healing by triggering reepithelization and collagen maturation and modulating inflammation and oxidative stress.
•Defocused high-power diode laser (DHPL) is a promising therapy for wound healing•DHPL effect on skin repair had never been evaluated an animal model study•DHPL was as effective as low-level laser therapy in accelerating skin repair•DHPL triggered reepithelization and collagen maturation during skin repair•DHPL modulated inflammation and oxidative stress during skin repair</description><identifier>ISSN: 1011-1344</identifier><identifier>EISSN: 1873-2682</identifier><identifier>DOI: 10.1016/j.jphotobiol.2021.112332</identifier><identifier>PMID: 34653929</identifier><language>eng</language><publisher>Switzerland: Elsevier B.V</publisher><subject>Animal models ; Animals ; Collagen ; Collagen - metabolism ; Cytokines ; Cytokines - metabolism ; Defocused high-power laser ; Diode lasers ; Epithelium - growth & development ; Epithelium - radiation effects ; Healing ; IL-1β ; Inflammation ; Inflammation - prevention & control ; Interleukin 10 ; Laser Therapy - methods ; Lasers ; Low-level laser therapy ; Male ; Maturation ; Oxidation-Reduction ; Oxidative stress ; Oxidative Stress - radiation effects ; Photobiomodulation ; Rats ; Rats, Wistar ; Redox properties ; Repair ; Rodents ; Semiconductor lasers ; Skin ; Skin - metabolism ; Skin - physiopathology ; Tumor necrosis factor-α ; Wound Healing - radiation effects</subject><ispartof>Journal of photochemistry and photobiology. B, Biology, 2021-12, Vol.225, p.112332-112332, Article 112332</ispartof><rights>2021 Elsevier B.V.</rights><rights>Copyright © 2021 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier BV Dec 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-a627321b3efcbf416b47b94e2aeb1be33ec7b2222c77986e39b87cd5700887723</citedby><cites>FETCH-LOGICAL-c402t-a627321b3efcbf416b47b94e2aeb1be33ec7b2222c77986e39b87cd5700887723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jphotobiol.2021.112332$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34653929$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mármora, Belkiss Câmara</creatorcontrib><creatorcontrib>Brochado, Fernanda Thomé</creatorcontrib><creatorcontrib>Schmidt, Tuany Rafaelli</creatorcontrib><creatorcontrib>Santos, Lucas Gonçalves</creatorcontrib><creatorcontrib>Araújo, Aurigena Antunes de</creatorcontrib><creatorcontrib>Medeiros, Caroline Addison Carvalho Xavier de</creatorcontrib><creatorcontrib>Ribeiro, Susana Barbosa</creatorcontrib><creatorcontrib>Martins, Marco Antonio Trevizani</creatorcontrib><creatorcontrib>Pilar, Emily Ferreira Salles</creatorcontrib><creatorcontrib>Wagner, Vivian Petersen</creatorcontrib><creatorcontrib>Martins, Manoela Domingues</creatorcontrib><title>Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation</title><title>Journal of photochemistry and photobiology. B, Biology</title><addtitle>J Photochem Photobiol B</addtitle><description>Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level laser therapy. Male Wistar rats were divided into 5 groups: Negative control; Sham; 0.1 W laser (L0.1 W); DHPL Dual 1 W (DHPLD1 W); and DHPL Dual 2 W (DHPLD2 W). Rats were euthanized on days 3, 5, 10, 14 and 21. Clinical, morphological, PicroSirus, oxidative stress (MDA, SOD and GSH) and cytokines (IL-1β, IL-10 and TNF-α) analyses were performed. A faster clinical repair was observed in all laser groups at D10 and D14. DHPLD1 W exhibited lower inflammation and better reepithelization compared to other groups at D10. DHPL protocols modulated oxidative stress by decreasing MDA and increasing SOD and GSH. Collagen maturation was triggered by all protocols tested and L0.1 W modulated cytokines release (IL-1β and TNF-α) at D3. In conclusion, DHPL, especially DHPL1 W protocol, accelerated skin healing by triggering reepithelization and collagen maturation and modulating inflammation and oxidative stress.
•Defocused high-power diode laser (DHPL) is a promising therapy for wound healing•DHPL effect on skin repair had never been evaluated an animal model study•DHPL was as effective as low-level laser therapy in accelerating skin repair•DHPL triggered reepithelization and collagen maturation during skin repair•DHPL modulated inflammation and oxidative stress during skin repair</description><subject>Animal models</subject><subject>Animals</subject><subject>Collagen</subject><subject>Collagen - metabolism</subject><subject>Cytokines</subject><subject>Cytokines - metabolism</subject><subject>Defocused high-power laser</subject><subject>Diode lasers</subject><subject>Epithelium - growth & development</subject><subject>Epithelium - radiation effects</subject><subject>Healing</subject><subject>IL-1β</subject><subject>Inflammation</subject><subject>Inflammation - prevention & control</subject><subject>Interleukin 10</subject><subject>Laser Therapy - methods</subject><subject>Lasers</subject><subject>Low-level laser therapy</subject><subject>Male</subject><subject>Maturation</subject><subject>Oxidation-Reduction</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - radiation effects</subject><subject>Photobiomodulation</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Redox properties</subject><subject>Repair</subject><subject>Rodents</subject><subject>Semiconductor lasers</subject><subject>Skin</subject><subject>Skin - metabolism</subject><subject>Skin - physiopathology</subject><subject>Tumor necrosis factor-α</subject><subject>Wound Healing - radiation effects</subject><issn>1011-1344</issn><issn>1873-2682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1DAUhiMEoqXwCsgSGzYZfEnsZAltuUiVKiGQ2Fm-nEwcnDjYDggehyfFwwxUYsPZ-Nfx9_vY_qsKEbwjmPAX025ax5CDdsHvKKZkRwhljN6rzkknWE15R-8XjQmpCWuas-pRShMu1XLxsDpjDW9ZT_vz6ucVDMFsCSwa3X6s1_ANIrIuWEBepaKVMeAhqgwJpc9uQRFW5SIqSqF5i24BNBfcozzGsO1H9P766vYTSrlYDjubV9mFQi-2eGF1eQTvftw1TfBe7WFBFtaQ3O9-ym4-GR9XDwblEzw5rRfVx9fXHy7f1je3b95dvrypTYNprhWnglGiGQxGDw3huhG6b4Aq0EQDY2CEpqWMEH3HgfW6E8a2AuOuE4Kyi-r58dw1hi8bpCxnl8rbvVogbEnStqMd4bghBX32DzqFLS7ldpJyinvectwXqjtSJoaUIgxyjW5W8bskWB5ylJO8y1EecpTHHIv16WnApmewf41_givAqyMA5Ue-OogyGQeLAesimCxtcP-f8guUKbbc</recordid><startdate>202112</startdate><enddate>202112</enddate><creator>Mármora, Belkiss Câmara</creator><creator>Brochado, Fernanda Thomé</creator><creator>Schmidt, Tuany Rafaelli</creator><creator>Santos, Lucas Gonçalves</creator><creator>Araújo, Aurigena Antunes de</creator><creator>Medeiros, Caroline Addison Carvalho Xavier de</creator><creator>Ribeiro, Susana Barbosa</creator><creator>Martins, Marco Antonio Trevizani</creator><creator>Pilar, Emily Ferreira Salles</creator><creator>Wagner, Vivian Petersen</creator><creator>Martins, Manoela Domingues</creator><general>Elsevier B.V</general><general>Elsevier BV</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>202112</creationdate><title>Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation</title><author>Mármora, Belkiss Câmara ; Brochado, Fernanda Thomé ; Schmidt, Tuany Rafaelli ; Santos, Lucas Gonçalves ; Araújo, Aurigena Antunes de ; Medeiros, Caroline Addison Carvalho Xavier de ; Ribeiro, Susana Barbosa ; Martins, Marco Antonio Trevizani ; Pilar, Emily Ferreira Salles ; Wagner, Vivian Petersen ; Martins, Manoela Domingues</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-a627321b3efcbf416b47b94e2aeb1be33ec7b2222c77986e39b87cd5700887723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Animal models</topic><topic>Animals</topic><topic>Collagen</topic><topic>Collagen - metabolism</topic><topic>Cytokines</topic><topic>Cytokines - metabolism</topic><topic>Defocused high-power laser</topic><topic>Diode lasers</topic><topic>Epithelium - growth & development</topic><topic>Epithelium - radiation effects</topic><topic>Healing</topic><topic>IL-1β</topic><topic>Inflammation</topic><topic>Inflammation - prevention & control</topic><topic>Interleukin 10</topic><topic>Laser Therapy - methods</topic><topic>Lasers</topic><topic>Low-level laser therapy</topic><topic>Male</topic><topic>Maturation</topic><topic>Oxidation-Reduction</topic><topic>Oxidative stress</topic><topic>Oxidative Stress - radiation effects</topic><topic>Photobiomodulation</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Redox properties</topic><topic>Repair</topic><topic>Rodents</topic><topic>Semiconductor lasers</topic><topic>Skin</topic><topic>Skin - metabolism</topic><topic>Skin - physiopathology</topic><topic>Tumor necrosis factor-α</topic><topic>Wound Healing - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mármora, Belkiss Câmara</creatorcontrib><creatorcontrib>Brochado, Fernanda Thomé</creatorcontrib><creatorcontrib>Schmidt, Tuany Rafaelli</creatorcontrib><creatorcontrib>Santos, Lucas Gonçalves</creatorcontrib><creatorcontrib>Araújo, Aurigena Antunes de</creatorcontrib><creatorcontrib>Medeiros, Caroline Addison Carvalho Xavier de</creatorcontrib><creatorcontrib>Ribeiro, Susana Barbosa</creatorcontrib><creatorcontrib>Martins, Marco Antonio Trevizani</creatorcontrib><creatorcontrib>Pilar, Emily Ferreira Salles</creatorcontrib><creatorcontrib>Wagner, Vivian Petersen</creatorcontrib><creatorcontrib>Martins, Manoela Domingues</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of photochemistry and photobiology. B, Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mármora, Belkiss Câmara</au><au>Brochado, Fernanda Thomé</au><au>Schmidt, Tuany Rafaelli</au><au>Santos, Lucas Gonçalves</au><au>Araújo, Aurigena Antunes de</au><au>Medeiros, Caroline Addison Carvalho Xavier de</au><au>Ribeiro, Susana Barbosa</au><au>Martins, Marco Antonio Trevizani</au><au>Pilar, Emily Ferreira Salles</au><au>Wagner, Vivian Petersen</au><au>Martins, Manoela Domingues</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation</atitle><jtitle>Journal of photochemistry and photobiology. B, Biology</jtitle><addtitle>J Photochem Photobiol B</addtitle><date>2021-12</date><risdate>2021</risdate><volume>225</volume><spage>112332</spage><epage>112332</epage><pages>112332-112332</pages><artnum>112332</artnum><issn>1011-1344</issn><eissn>1873-2682</eissn><abstract>Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level laser therapy. Male Wistar rats were divided into 5 groups: Negative control; Sham; 0.1 W laser (L0.1 W); DHPL Dual 1 W (DHPLD1 W); and DHPL Dual 2 W (DHPLD2 W). Rats were euthanized on days 3, 5, 10, 14 and 21. Clinical, morphological, PicroSirus, oxidative stress (MDA, SOD and GSH) and cytokines (IL-1β, IL-10 and TNF-α) analyses were performed. A faster clinical repair was observed in all laser groups at D10 and D14. DHPLD1 W exhibited lower inflammation and better reepithelization compared to other groups at D10. DHPL protocols modulated oxidative stress by decreasing MDA and increasing SOD and GSH. Collagen maturation was triggered by all protocols tested and L0.1 W modulated cytokines release (IL-1β and TNF-α) at D3. In conclusion, DHPL, especially DHPL1 W protocol, accelerated skin healing by triggering reepithelization and collagen maturation and modulating inflammation and oxidative stress.
•Defocused high-power diode laser (DHPL) is a promising therapy for wound healing•DHPL effect on skin repair had never been evaluated an animal model study•DHPL was as effective as low-level laser therapy in accelerating skin repair•DHPL triggered reepithelization and collagen maturation during skin repair•DHPL modulated inflammation and oxidative stress during skin repair</abstract><cop>Switzerland</cop><pub>Elsevier B.V</pub><pmid>34653929</pmid><doi>10.1016/j.jphotobiol.2021.112332</doi><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1011-1344 |
| ispartof | Journal of photochemistry and photobiology. B, Biology, 2021-12, Vol.225, p.112332-112332, Article 112332 |
| issn | 1011-1344 1873-2682 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2582816041 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animal models Animals Collagen Collagen - metabolism Cytokines Cytokines - metabolism Defocused high-power laser Diode lasers Epithelium - growth & development Epithelium - radiation effects Healing IL-1β Inflammation Inflammation - prevention & control Interleukin 10 Laser Therapy - methods Lasers Low-level laser therapy Male Maturation Oxidation-Reduction Oxidative stress Oxidative Stress - radiation effects Photobiomodulation Rats Rats, Wistar Redox properties Repair Rodents Semiconductor lasers Skin Skin - metabolism Skin - physiopathology Tumor necrosis factor-α Wound Healing - radiation effects |
| title | Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T05%3A31%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Defocused%20high-power%20diode%20laser%20accelerates%20skin%20repair%20in%20a%20murine%20model%20through%20REDOX%20state%20modulation%20and%20reepithelization%20and%20collagen%20deposition%20stimulation&rft.jtitle=Journal%20of%20photochemistry%20and%20photobiology.%20B,%20Biology&rft.au=M%C3%A1rmora,%20Belkiss%20C%C3%A2mara&rft.date=2021-12&rft.volume=225&rft.spage=112332&rft.epage=112332&rft.pages=112332-112332&rft.artnum=112332&rft.issn=1011-1344&rft.eissn=1873-2682&rft_id=info:doi/10.1016/j.jphotobiol.2021.112332&rft_dat=%3Cproquest_cross%3E2620965609%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2620965609&rft_id=info:pmid/34653929&rft_els_id=S1011134421002116&rfr_iscdi=true |