Dynamic-Inspired Perspective on the Molecular Inhibitor of Tau Aggregation by Glucose Gallates Based on Human Neurons

A molecular inhibitor of tau protein aggregation offers an attractive therapeutic possibility as disease-modifying treatment of Alzheimer’s disease. However, the ineffectiveness as well as adjoint toxicity due to superficial understanding of the inhibition mechanism has hindered drug development. Co...

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Veröffentlicht in:	ACS chemical neuroscience 2021-11, Vol.12 (21), p.4162-4174
Hauptverfasser:	Hu, Yuan, Yang, Danjing, Tu, Ying, Chai, Keke, Chu, Lei, Shi, Shuo, Yao, Tianming
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease Glucose Humans Ligands Neurons tau Proteins
Online-Zugang:	Volltext
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