Challenges in Chronic Myeloid Leukemia Management in South America
Purpose of Review Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a challenge and interfere with the best practices and results of CML treatment. Th...
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| Veröffentlicht in: | Current hematologic malignancy reports 2021-10, Vol.16 (5), p.440-447 |
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| container_title | Current hematologic malignancy reports |
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| creator | Pagnano, Katia B. Varela, Ana Ines Pavlovsky, Carolina Bendit, Israel Funke, Vaneuza A. M. Polo, Virginia Abello |
| description | Purpose of Review
Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a challenge and interfere with the best practices and results of CML treatment. This review points out the main challenges in CML management in South America.
Recent Findings.
In this review, we describe the access to tyrosine kinase inhibitors and monitoring in different countries of South America. We also address the ongoing discontinuation trials, the progress, and limitations of hematopoietic stem cell transplantation in the last years.
Summary
There are still many challenges for achieving the best outcomes for CML patients in South America. The continuous efforts to provide continuous education, access to tyrosine kinase inhibitors, and monitoring, providing reference centers for CML management and hematopoietic stem cell transplantation may improve patients’ outcomes. |
| doi_str_mv | 10.1007/s11899-021-00654-0 |
| format | Article |
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Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a challenge and interfere with the best practices and results of CML treatment. This review points out the main challenges in CML management in South America.
Recent Findings.
In this review, we describe the access to tyrosine kinase inhibitors and monitoring in different countries of South America. We also address the ongoing discontinuation trials, the progress, and limitations of hematopoietic stem cell transplantation in the last years.
Summary
There are still many challenges for achieving the best outcomes for CML patients in South America. The continuous efforts to provide continuous education, access to tyrosine kinase inhibitors, and monitoring, providing reference centers for CML management and hematopoietic stem cell transplantation may improve patients’ outcomes.</description><identifier>ISSN: 1558-8211</identifier><identifier>EISSN: 1558-822X</identifier><identifier>DOI: 10.1007/s11899-021-00654-0</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Chronic Myeloid Leukemias (MJ Mauro and G Saglio ; Geriatrics/Gerontology ; Hematology ; Medicine ; Medicine & Public Health ; Oncology ; Section Editors ; Topical Collection on Chronic Myeloid Leukemias</subject><ispartof>Current hematologic malignancy reports, 2021-10, Vol.16 (5), p.440-447</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c324t-ab5a322d1d9d361eacb6d228419c6f39db94c7538fc48d595917cc2b37095a873</citedby><cites>FETCH-LOGICAL-c324t-ab5a322d1d9d361eacb6d228419c6f39db94c7538fc48d595917cc2b37095a873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11899-021-00654-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11899-021-00654-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids></links><search><creatorcontrib>Pagnano, Katia B.</creatorcontrib><creatorcontrib>Varela, Ana Ines</creatorcontrib><creatorcontrib>Pavlovsky, Carolina</creatorcontrib><creatorcontrib>Bendit, Israel</creatorcontrib><creatorcontrib>Funke, Vaneuza A. M.</creatorcontrib><creatorcontrib>Polo, Virginia Abello</creatorcontrib><title>Challenges in Chronic Myeloid Leukemia Management in South America</title><title>Current hematologic malignancy reports</title><addtitle>Curr Hematol Malig Rep</addtitle><description>Purpose of Review
Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a challenge and interfere with the best practices and results of CML treatment. This review points out the main challenges in CML management in South America.
Recent Findings.
In this review, we describe the access to tyrosine kinase inhibitors and monitoring in different countries of South America. We also address the ongoing discontinuation trials, the progress, and limitations of hematopoietic stem cell transplantation in the last years.
Summary
There are still many challenges for achieving the best outcomes for CML patients in South America. The continuous efforts to provide continuous education, access to tyrosine kinase inhibitors, and monitoring, providing reference centers for CML management and hematopoietic stem cell transplantation may improve patients’ outcomes.</description><subject>Chronic Myeloid Leukemias (MJ Mauro and G Saglio</subject><subject>Geriatrics/Gerontology</subject><subject>Hematology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Oncology</subject><subject>Section Editors</subject><subject>Topical Collection on Chronic Myeloid Leukemias</subject><issn>1558-8211</issn><issn>1558-822X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kD1PwzAQQC0EEqXwB5gyshh8_kjssURQkFoxABKb5dhOm5KPYidD_z0pQYxMd8N7J91D6BrILRCS3UUAqRQmFDAhqeCYnKAZCCGxpPTj9G8HOEcXMe4I4RwIm6H7fGvq2rcbH5OqTfJt6NrKJuuDr7vKJSs_fPqmMsnatGbjG9_2R-y1G_ptsmh8qKy5RGelqaO_-p1z9P748JY_4dXL8jlfrLBllPfYFMIwSh045VgK3tgidZRKDsqmJVOuUNxmgsnScumEEgoya2nBMqKEkRmbo5vp7j50X4OPvW6qaH1dm9Z3Q9RUSCqB05SNKJ1QG7oYgy_1PlSNCQcNRB-D6SmYHoPpn2CajBKbpDjCY5Cgd90Q2vGl_6xvpAJtFw</recordid><startdate>20211001</startdate><enddate>20211001</enddate><creator>Pagnano, Katia B.</creator><creator>Varela, Ana Ines</creator><creator>Pavlovsky, Carolina</creator><creator>Bendit, Israel</creator><creator>Funke, Vaneuza A. M.</creator><creator>Polo, Virginia Abello</creator><general>Springer US</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20211001</creationdate><title>Challenges in Chronic Myeloid Leukemia Management in South America</title><author>Pagnano, Katia B. ; Varela, Ana Ines ; Pavlovsky, Carolina ; Bendit, Israel ; Funke, Vaneuza A. M. ; Polo, Virginia Abello</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c324t-ab5a322d1d9d361eacb6d228419c6f39db94c7538fc48d595917cc2b37095a873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Chronic Myeloid Leukemias (MJ Mauro and G Saglio</topic><topic>Geriatrics/Gerontology</topic><topic>Hematology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Oncology</topic><topic>Section Editors</topic><topic>Topical Collection on Chronic Myeloid Leukemias</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pagnano, Katia B.</creatorcontrib><creatorcontrib>Varela, Ana Ines</creatorcontrib><creatorcontrib>Pavlovsky, Carolina</creatorcontrib><creatorcontrib>Bendit, Israel</creatorcontrib><creatorcontrib>Funke, Vaneuza A. M.</creatorcontrib><creatorcontrib>Polo, Virginia Abello</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current hematologic malignancy reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pagnano, Katia B.</au><au>Varela, Ana Ines</au><au>Pavlovsky, Carolina</au><au>Bendit, Israel</au><au>Funke, Vaneuza A. M.</au><au>Polo, Virginia Abello</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Challenges in Chronic Myeloid Leukemia Management in South America</atitle><jtitle>Current hematologic malignancy reports</jtitle><stitle>Curr Hematol Malig Rep</stitle><date>2021-10-01</date><risdate>2021</risdate><volume>16</volume><issue>5</issue><spage>440</spage><epage>447</epage><pages>440-447</pages><issn>1558-8211</issn><eissn>1558-822X</eissn><abstract>Purpose of Review
Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a challenge and interfere with the best practices and results of CML treatment. This review points out the main challenges in CML management in South America.
Recent Findings.
In this review, we describe the access to tyrosine kinase inhibitors and monitoring in different countries of South America. We also address the ongoing discontinuation trials, the progress, and limitations of hematopoietic stem cell transplantation in the last years.
Summary
There are still many challenges for achieving the best outcomes for CML patients in South America. The continuous efforts to provide continuous education, access to tyrosine kinase inhibitors, and monitoring, providing reference centers for CML management and hematopoietic stem cell transplantation may improve patients’ outcomes.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s11899-021-00654-0</doi><tpages>8</tpages></addata></record> |
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| language | eng |
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| subjects | Chronic Myeloid Leukemias (MJ Mauro and G Saglio Geriatrics/Gerontology Hematology Medicine Medicine & Public Health Oncology Section Editors Topical Collection on Chronic Myeloid Leukemias |
| title | Challenges in Chronic Myeloid Leukemia Management in South America |
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