Vitiligo Skin T Cells Are Prone to Produce Type 1 and Type 2 Cytokines to Induce Melanocyte Dysfunction and Epidermal Inflammatory Response Through Jak Signaling

Vitiligo is a T cell–mediated inflammatory skin disorder characterized by the loss of epidermal melanocytes. However, the contribution of melanocytes to the physiopathology of the disease in response to the T-cell microenvironment remains unclear. Here, using NanoString technology and multiplex ELIS...

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Veröffentlicht in:Journal of investigative dermatology 2022-04, Vol.142 (4), p.1194-1205.e7
Hauptverfasser: Martins, Christina, Migayron, Laure, Drullion, Claire, Jacquemin, Clément, Lucchese, Fabienne, Rambert, Jérôme, Merhi, Ribal, Michon, Pauline, Taieb, Alain, Rezvani, Hamid-Reza, de Rinaldis, Emanuele, Seneschal, Julien, Boniface, Katia
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Sprache:eng
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