Explicating the molecular level drug-polymer interactions at the interface of supersaturated solution of the model drug: Albendazole

Supersaturation as a formulation principle relates to the aqueous solubility of poorly soluble drugs in solution . However, supersaturation state of drugs tends to crystallize because of its thermodynamic instability thereby compromising the solubility and biopharmaceutical performance of drugs. The...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2021-12, Vol.167, p.106014-106014, Article 106014
Hauptverfasser:	Joshi, Prachi, Mallepogu, Prabhakar, Kaur, Harpreet, Singh, Ridhima, Sodhi, Ikjot, Samal, Sanjaya K., Jena, Kailash C., Sangamwar, Abhay T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Air-water interface Drug-polymer interactions FTIR NMR Precipitation inhibitors Sum frequency generation spectroscopy Supersaturation
Online-Zugang:	Volltext
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