Preclinical and clinical studies to evaluate cutaneous biodistribution, safety and efficacy of UV filters encapsulated in mesoporous silica SBA-15

[Display omitted] Innovative technologies have been designed to improve efficacy and safety of chemical UV filters. Encapsulation can enhance efficacy and reduce transdermal permeation and systemic exposure. The aims of this work were (i) to determine the cutaneous biodistribution of avobenzone (AVO...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2021-12, Vol.169, p.113-124
Hauptverfasser:	Daneluti, André Luis Máximo, Guerra, Lucas Offenbecker, Velasco, Maria Valéria Robles, do Rosário Matos, Jivaldo, Baby, André Rolim, Kalia, Yogeshvar N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Animals Avobenzone Benzophenones - pharmacokinetics Biodistribution Cinnamates - pharmacokinetics Clinical safety Drug Compounding - methods Drug Evaluation, Preclinical Human skin Humans In vivo SPF Mesoporous silica Micropore Filters Octyl methoxycinnamate Oxybenzone Propiophenones - pharmacokinetics SBA-15 Silicon Dioxide - pharmacology Skin Absorption Stick incorporated UV filters Sun Protection Factor Sunscreening Agents - pharmacokinetics Swine Tissue Distribution
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