The long non-coding RNA ET-20 mediates EMT by impairing desmosomes in breast cancer cells

The vast majority of breast cancer-associated deaths are due to metastatic spread of cancer cells, a process aided by epithelial-to-mesenchymal transition (EMT). Mounting evidence has indicated that long non-coding RNAs (lncRNAs) also contribute to tumor progression. We report the identification of...

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Veröffentlicht in:	Journal of cell science 2021-11, Vol.134 (21)
Hauptverfasser:	Saxena, Meera, Hisano, Mizue, Neutzner, Melanie, Diepenbruck, Maren, Ivanek, Robert, Sharma, Kirti, Kalathur, Ravi K R, Bürglin, Thomas R, Risoli, Salvatore, Christofori, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - genetics Cell Line, Tumor Desmosomes - genetics Epithelial-Mesenchymal Transition - genetics Female Gene Expression Regulation, Neoplastic Humans Mice Neoplasm Invasiveness - genetics RNA, Long Noncoding - genetics SOXC Transcription Factors
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