Probing IgG1 FC–Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

In this study, NMR and molecular dynamics simulations were employed to study IgG1 FC binding to multimodal surfaces. Gold nanoparticles functionalized with two multimodal cation-exchange ligands (Capto and Nuvia) were synthesized and employed to carry out solution-phase NMR experiments with the FC....

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Veröffentlicht in:	Langmuir 2021-10, Vol.37 (41), p.12188-12203
Hauptverfasser:	Gudhka, Ronak B, Vats, Mayank, Bilodeau, Camille L, McCallum, Scott A, McCoy, Mark A, Roush, David J, Snyder, Mark A, Cramer, Steven M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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