Radiosynthesis of 1-(2-[18F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol

The kynurenine pathway (KP) is a primary route for tryptophan metabolism. Evidence strongly suggests that metabolites of the KP play a vital role in tumor proliferation, epilepsy, neurodegenerative diseases, and psychiatric illnesses due to their immune-modulatory, neuro-modulatory, and neurotoxic e...

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Veröffentlicht in:	Journal of visualized experiments 2021-09 (175)
Hauptverfasser:	Yue, Xuyi, Nikam, Rahul M., Kecskemethy, Heidi H., Kandula, Vinay V. R., Falchek, Stephen J., Averill, Lauren W., Langhans, Sigrid A.
Format:	Artikel
Sprache:	eng
Schlagworte:	epilepsy genetically modified organisms half life kynurenine pathway metabolism metabolites neoplasms neurotoxicity positron-emission tomography solvents tryptophan xenotransplantation
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