A preliminary study investigating the detection of lymphovascular invasion in germ cell tumors of the testis with double staining for OCT4/CD34

Lymphovascular invasion (LVI) is a relevant prognostic factor in germ cell tumors of the testis (GCTT) and it has been included in the AJCC staging system. Nevertheless, its histological assessment is challenging, with low/moderate interobserver agreement also among expert uropathologists. Few studi...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2021-11, Vol.227, p.153637-153637, Article 153637
Hauptverfasser:	Ricci, Costantino, Franceschini, Tania, Giunchi, Francesca, Borsato, Matteo, Mollica, Veronica, Massari, Francesco, Fiorentino, Michelangelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, CD34 - analysis Biomarkers, Tumor - analysis Carcinoma, Embryonal - chemistry Carcinoma, Embryonal - pathology Double staining Germ cell tumors of the testis Humans Immunohistochemistry Lymphatic Vessels - chemistry Lymphatic Vessels - pathology Lymphovascular invasion Male Middle Aged Neoplasm Invasiveness Neoplasm Staging Neoplasms, Complex and Mixed - chemistry Neoplasms, Complex and Mixed - pathology Neoplasms, Germ Cell and Embryonal - chemistry Neoplasms, Germ Cell and Embryonal - pathology OCT4 Octamer Transcription Factor-3 - analysis Predictive Value of Tests Retrospective Studies Seminoma - chemistry Seminoma - pathology Staging Testicular Neoplasms - chemistry Testicular Neoplasms - pathology Young Adult
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