Ferroptosis and NRF2: an emerging battlefield in the neurodegeneration of Alzheimer's disease

Ferroptosis is an iron- and lipid peroxidation-dependent cell death modality and emerging evidence indicates that ferroptosis has great explanatory potential for neuronal loss and associated CNS dysfunction in a range of neurodegenerative diseases (e.g., Alzheimer's, Parkinson's and Huntin...

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Veröffentlicht in:	Essays in biochemistry 2021-12, Vol.65 (7), p.925-940
Hauptverfasser:	Lane, Darius J R, Metselaar, Billie, Greenough, Mark, Bush, Ashley I, Ayton, Scott J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Ferroptosis Humans Lipid Peroxidation Lipid Peroxides NF-E2-Related Factor 2 - metabolism
Online-Zugang:	Volltext
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