Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

Extracellular vesicles (EVs) can be functionalized to display specific protein receptors on their surface. However, surface-display technology typically labels only a small fraction of the EV population. Here, we show that the joint display of two different therapeutically relevant protein receptors...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	NATURE BIOMEDICAL ENGINEERING 2021-09, Vol.5 (9), p.1084-1098
Hauptverfasser:	Gupta, Dhanu, Wiklander, Oscar P. B., Görgens, André, Conceição, Mariana, Corso, Giulia, Liang, Xiuming, Seow, Yiqi, Balusu, Sriram, Feldin, Ulrika, Bostancioglu, Beklem, Jawad, Rim, Mamand, Doste R., Lee, Yi Xin Fiona, Hean, Justin, Mäger, Imre, Roberts, Thomas C., Gustafsson, Manuela, Mohammad, Dara K., Sork, Helena, Backlund, Alexandra, Lundin, Per, de Fougerolles, Antonin, Smith, C. I. Edvard, Wood, Matthew J. A., Vandenbroucke, Roosmarijn E., Nordin, Joel Z., El-Andaloussi, Samir
Format:	Artikel
Sprache:	eng
Schlagworte:	13/109 13/21 13/31 13/95 14 14/28 14/34 14/5 38/39 38/90 42/44 59/5 631/61 631/61/350/354 64/60 Adaptor proteins Animal models Animals Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biopharmaceuticals Cytokines Decoys Display devices Extracellular Vesicles Genetic engineering Inflammation Interleukin 6 Mice Neuroinflammatory Diseases Oligomerization Phenotypes Proteins Receptors Syndecan Tumor necrosis factor receptors Tumor Necrosis Factor-alpha Tumor necrosis factor-TNF Tumor necrosis factor-α Tumors Vesicles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!