DNA Origami Frameworks Enabled Self‐Protective siRNA Delivery for Dual Enhancement of Chemo‐Photothermal Combination Therapy

Although chemotherapy and photothermal therapy are widely used to combat cancer, their efficacy is often limited by multidrug resistance. Small interfering RNAs (siRNAs) have ability to suppress the expression of target genes, which has been extensively employed for combating the multidrug resistanc...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2021-11, Vol.17 (46), p.e2101780-n/a
Hauptverfasser:	Xu, Tingting, Yu, Sha, Sun, Yao, Wu, Shaojun, Gao, Di, Wang, Mingyang, Wang, Zhenzhen, Tian, Ye, Min, Qianhao, Zhu, Jun‐Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	3D nanoscaffolds Biocompatibility Cancer Cancer therapies Cell Line, Tumor Combination therapy Combinatorial analysis Connective tissues Deoxyribonucleic acid DNA DNA origami Doxorubicin dual sensitization Gene expression Growth factors Heat shock proteins Hyperthermia Hyperthermia, Induced Nanorods Nanotechnology Phototherapy Photothermal Therapy RNA, Small Interfering siRNAs delivery Toxicity
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