Rhodium-Catalyzed Annulation of Phenacyl Ammonium Salts with Propargylic Alcohols via a Sequential Dual C–H and a C–C Bond Activation: Modular Entry to Diverse Isochromenones

Given their omnipresence in natural products and pharmaceuticals, isochromenone congeners are one of the most privileged scaffolds to synthetic chemists. Disclosed herein is a dual (ortho/meta) C–H and C–C activation of phenacyl ammonium salts (acylammonium as traceless directing group) toward annul...

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Veröffentlicht in:Organic letters 2021-10, Vol.23 (20), p.7888-7893
Hauptverfasser: Reddy Singam, Maneesh Kumar, Suri Babu, Undamatla, Suresh, Vavilapalli, Nanubolu, Jagadeesh Babu, Sridhar Reddy, Maddi
Format: Artikel
Sprache:eng
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