Rhodium-Catalyzed Annulation of Phenacyl Ammonium Salts with Propargylic Alcohols via a Sequential Dual C–H and a C–C Bond Activation: Modular Entry to Diverse Isochromenones
Given their omnipresence in natural products and pharmaceuticals, isochromenone congeners are one of the most privileged scaffolds to synthetic chemists. Disclosed herein is a dual (ortho/meta) C–H and C–C activation of phenacyl ammonium salts (acylammonium as traceless directing group) toward annul...
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Veröffentlicht in: | Organic letters 2021-10, Vol.23 (20), p.7888-7893 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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