Hepatotoxicity induced by chronic suppurative otitis media in rats and effects of ceftazidime and amikacin on it

Chronic suppurative otitis media (CSOM) is the chronic inflammation with perforation of middle ear. If CSOM is not treated, it may cause secondary inflammation of liver with elevated liver enzymes and histological changes. Present study is aimed to observe the hepatotoxic effects due chronic suppura...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2021-05, Vol.34 (3(Special)), p.1243-1248
Hauptverfasser:	Mehboob, Shafaque, Saleem, Darakhshan M, Mehjabeen, -, Mehboob, Moona, Jahan, Noor, Perveen, Shaheen, Tariq Rafi, S M, Anser, Humaira, Owais, Farah
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - metabolism Alkaline Phosphatase - metabolism Amikacin - pharmacology Amikacin - therapeutic use Animals Anti-Bacterial Agents - therapeutic use Aspartate Aminotransferases - metabolism Bilirubin - metabolism Ceftazidime - pharmacology Ceftazidime - therapeutic use Chronic Disease gamma-Glutamyltransferase - metabolism Liver - drug effects Liver - metabolism Liver Diseases - etiology Liver Diseases - metabolism Liver Diseases - pathology Otitis Media, Suppurative - complications Otitis Media, Suppurative - drug therapy Rats Treatment Outcome
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