Embryonic Steroids Control Developmental Programming of Energy Balance

Glucose is a major energy source for growth. At birth, neonates must change their energy source from maternal supply to its own glucose production. The mechanism of this transition has not been clearly elucidated. To evaluate the possible roles of steroids in this transition, here we examine the def...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2021-12, Vol.162 (12)
Hauptverfasser:	Monica Shih, Meng-Chun, Huang, Chen-Che Jeff, Chu, Hsueh-Ping, Hsu, Nai-Chi, Chung, Bon-chu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Blood Blood glucose Cholesterol Side-Chain Cleavage Enzyme - genetics Cholesterol Side-Chain Cleavage Enzyme - metabolism Cholesterol Side-Chain Cleavage Enzyme - physiology Cytochrome P450 Cytochromes P450 Dexamethasone - pharmacology Embryo, Mammalian Embryonic Development - drug effects Embryonic Development - genetics Embryos Endocrinology Energy balance Energy Metabolism - drug effects Energy Metabolism - genetics Energy sources Female Fetuses Gene expression Genes Glucocorticoids Gluconeogenesis Gluconeogenesis - drug effects Gluconeogenesis - genetics Glucose Glycogen Glycogen - metabolism Glycogens Homeostasis Insulin Insulin secretion Liver Male Mice Mice, 129 Strain Mice, Inbred C57BL Mice, Transgenic Neonates Pregnancy Prenatal Exposure Delayed Effects - genetics Prenatal Exposure Delayed Effects - metabolism Steroid hormones Steroids Steroids - biosynthesis Steroids - pharmacology Synthesis
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