Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study
Purpose Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function w...
Gespeichert in:
| Veröffentlicht in: | European archives of oto-rhino-laryngology 2022-05, Vol.279 (5), p.2223-2230 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2230 |
|---|---|
| container_issue | 5 |
| container_start_page | 2223 |
| container_title | European archives of oto-rhino-laryngology |
| container_volume | 279 |
| creator | Lu, Hongyi Su, Jun Chi, Wanlei Zou, Ting Yu, Mingqiang Wang, Kang |
| description | Purpose
Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function were investigated.
Methods
This prospective diagnostic study included patients visiting the ENT Department of our Hospital, between April and June 2021. Patients were grouped into Eustachian tube dysfunction (ETD) and control groups according to tympanometry diagnosis results. The diagnostic value of the T-ETDQ was evaluated using receiver-operating characteristic (ROC) curve analysis.
Results
There were 48 patients with Obstructive ETD and 24 patients without. The area under the ROC curve (AUC) of T-ETDQ was 0.898 (95% confidence interval [CI] 0.826–0.969), and the highest sensitivity and specificity were 76.7% and 86.7% respectively when the positive cutoff value was 4.72. The AUC of Eustachian tube score (ETS) was 0.731 (95% CI 0.625–0.837) and the highest sensitivity and specificity were 48.3% and 90.0% respectively when the positive cut-off value was 4.5. The ETS and T-ETDQ had kappa values of 0.311 and 0.585, respectively (
P
|
| doi_str_mv | 10.1007/s00405-021-07108-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2578151942</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2578151942</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-6f0d49132f7e98b9314f99111a8edc11c4727a457bac784ed9408cba818e10d23</originalsourceid><addsrcrecordid>eNp9kDFv2zAQhYkgReO6_QMZAo5Z2N6JlClmKxwnLRCgKKzOBEWdYhqy5IhiAP_7yHGaMdMt3z289zF2ifAdAfSPCKAgF5ChAI1QiMUZm6GSSiidLc7ZDIzUQimtL9iXGLcAkCsjP7MLqXIDqM2M1cs2dMG7lj-7NhHvGz5uiK9SHJ3fBNfxMlXE71Lnx9B3fO37IXSPfH2II-14KVbl7d8b7vh-6OOeJuiZeB3cY9fHMXgex1QfvrJPjWsjfXu7c_bvblUuf4mHP_e_lz8fhJdKj2LRQK0MyqzRZIrKSFSNMYjoCqo9op9maadyXTmvC0W1UVD4yhVYEEKdyTm7PuVOZZ4SxdHuQvTUtq6jPkWb5brAHI06otkJ9VPvOFBj90PYueFgEezRrj3ZtZNd-2rXLqanq7f8VO2ofn_5r3MC5AmI-6MlGuy2T0M3bf4o9gWo0oSz</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2578151942</pqid></control><display><type>article</type><title>Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Lu, Hongyi ; Su, Jun ; Chi, Wanlei ; Zou, Ting ; Yu, Mingqiang ; Wang, Kang</creator><creatorcontrib>Lu, Hongyi ; Su, Jun ; Chi, Wanlei ; Zou, Ting ; Yu, Mingqiang ; Wang, Kang</creatorcontrib><description>Purpose
Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function were investigated.
Methods
This prospective diagnostic study included patients visiting the ENT Department of our Hospital, between April and June 2021. Patients were grouped into Eustachian tube dysfunction (ETD) and control groups according to tympanometry diagnosis results. The diagnostic value of the T-ETDQ was evaluated using receiver-operating characteristic (ROC) curve analysis.
Results
There were 48 patients with Obstructive ETD and 24 patients without. The area under the ROC curve (AUC) of T-ETDQ was 0.898 (95% confidence interval [CI] 0.826–0.969), and the highest sensitivity and specificity were 76.7% and 86.7% respectively when the positive cutoff value was 4.72. The AUC of Eustachian tube score (ETS) was 0.731 (95% CI 0.625–0.837) and the highest sensitivity and specificity were 48.3% and 90.0% respectively when the positive cut-off value was 4.5. The ETS and T-ETDQ had kappa values of 0.311 and 0.585, respectively (
P
< 0.001 for both), showing both methods were comparable to tympanometry; however, T-ETDQ had more consistent results than ETS.
Conclusion
T-ETDQ can effectively quantify and evaluate ETD severity in adults, has a higher diagnostic value than ETS, making it a suitable diagnostic tool.</description><identifier>ISSN: 0937-4477</identifier><identifier>EISSN: 1434-4726</identifier><identifier>DOI: 10.1007/s00405-021-07108-6</identifier><identifier>PMID: 34590179</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acoustic Impedance Tests ; Adult ; Ear Diseases - diagnosis ; Eustachian Tube ; Head and Neck Surgery ; Humans ; Medicine ; Medicine & Public Health ; Neurosurgery ; Otorhinolaryngology ; Prospective Studies ; Reproducibility of Results ; Review Article</subject><ispartof>European archives of oto-rhino-laryngology, 2022-05, Vol.279 (5), p.2223-2230</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-6f0d49132f7e98b9314f99111a8edc11c4727a457bac784ed9408cba818e10d23</citedby><cites>FETCH-LOGICAL-c347t-6f0d49132f7e98b9314f99111a8edc11c4727a457bac784ed9408cba818e10d23</cites><orcidid>0000-0002-7755-7945</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00405-021-07108-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00405-021-07108-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34590179$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Hongyi</creatorcontrib><creatorcontrib>Su, Jun</creatorcontrib><creatorcontrib>Chi, Wanlei</creatorcontrib><creatorcontrib>Zou, Ting</creatorcontrib><creatorcontrib>Yu, Mingqiang</creatorcontrib><creatorcontrib>Wang, Kang</creatorcontrib><title>Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study</title><title>European archives of oto-rhino-laryngology</title><addtitle>Eur Arch Otorhinolaryngol</addtitle><addtitle>Eur Arch Otorhinolaryngol</addtitle><description>Purpose
Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function were investigated.
Methods
This prospective diagnostic study included patients visiting the ENT Department of our Hospital, between April and June 2021. Patients were grouped into Eustachian tube dysfunction (ETD) and control groups according to tympanometry diagnosis results. The diagnostic value of the T-ETDQ was evaluated using receiver-operating characteristic (ROC) curve analysis.
Results
There were 48 patients with Obstructive ETD and 24 patients without. The area under the ROC curve (AUC) of T-ETDQ was 0.898 (95% confidence interval [CI] 0.826–0.969), and the highest sensitivity and specificity were 76.7% and 86.7% respectively when the positive cutoff value was 4.72. The AUC of Eustachian tube score (ETS) was 0.731 (95% CI 0.625–0.837) and the highest sensitivity and specificity were 48.3% and 90.0% respectively when the positive cut-off value was 4.5. The ETS and T-ETDQ had kappa values of 0.311 and 0.585, respectively (
P
< 0.001 for both), showing both methods were comparable to tympanometry; however, T-ETDQ had more consistent results than ETS.
Conclusion
T-ETDQ can effectively quantify and evaluate ETD severity in adults, has a higher diagnostic value than ETS, making it a suitable diagnostic tool.</description><subject>Acoustic Impedance Tests</subject><subject>Adult</subject><subject>Ear Diseases - diagnosis</subject><subject>Eustachian Tube</subject><subject>Head and Neck Surgery</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neurosurgery</subject><subject>Otorhinolaryngology</subject><subject>Prospective Studies</subject><subject>Reproducibility of Results</subject><subject>Review Article</subject><issn>0937-4477</issn><issn>1434-4726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFv2zAQhYkgReO6_QMZAo5Z2N6JlClmKxwnLRCgKKzOBEWdYhqy5IhiAP_7yHGaMdMt3z289zF2ifAdAfSPCKAgF5ChAI1QiMUZm6GSSiidLc7ZDIzUQimtL9iXGLcAkCsjP7MLqXIDqM2M1cs2dMG7lj-7NhHvGz5uiK9SHJ3fBNfxMlXE71Lnx9B3fO37IXSPfH2II-14KVbl7d8b7vh-6OOeJuiZeB3cY9fHMXgex1QfvrJPjWsjfXu7c_bvblUuf4mHP_e_lz8fhJdKj2LRQK0MyqzRZIrKSFSNMYjoCqo9op9maadyXTmvC0W1UVD4yhVYEEKdyTm7PuVOZZ4SxdHuQvTUtq6jPkWb5brAHI06otkJ9VPvOFBj90PYueFgEezRrj3ZtZNd-2rXLqanq7f8VO2ofn_5r3MC5AmI-6MlGuy2T0M3bf4o9gWo0oSz</recordid><startdate>202205</startdate><enddate>202205</enddate><creator>Lu, Hongyi</creator><creator>Su, Jun</creator><creator>Chi, Wanlei</creator><creator>Zou, Ting</creator><creator>Yu, Mingqiang</creator><creator>Wang, Kang</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7755-7945</orcidid></search><sort><creationdate>202205</creationdate><title>Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study</title><author>Lu, Hongyi ; Su, Jun ; Chi, Wanlei ; Zou, Ting ; Yu, Mingqiang ; Wang, Kang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-6f0d49132f7e98b9314f99111a8edc11c4727a457bac784ed9408cba818e10d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acoustic Impedance Tests</topic><topic>Adult</topic><topic>Ear Diseases - diagnosis</topic><topic>Eustachian Tube</topic><topic>Head and Neck Surgery</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neurosurgery</topic><topic>Otorhinolaryngology</topic><topic>Prospective Studies</topic><topic>Reproducibility of Results</topic><topic>Review Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lu, Hongyi</creatorcontrib><creatorcontrib>Su, Jun</creatorcontrib><creatorcontrib>Chi, Wanlei</creatorcontrib><creatorcontrib>Zou, Ting</creatorcontrib><creatorcontrib>Yu, Mingqiang</creatorcontrib><creatorcontrib>Wang, Kang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of oto-rhino-laryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Hongyi</au><au>Su, Jun</au><au>Chi, Wanlei</au><au>Zou, Ting</au><au>Yu, Mingqiang</au><au>Wang, Kang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study</atitle><jtitle>European archives of oto-rhino-laryngology</jtitle><stitle>Eur Arch Otorhinolaryngol</stitle><addtitle>Eur Arch Otorhinolaryngol</addtitle><date>2022-05</date><risdate>2022</risdate><volume>279</volume><issue>5</issue><spage>2223</spage><epage>2230</epage><pages>2223-2230</pages><issn>0937-4477</issn><eissn>1434-4726</eissn><abstract>Purpose
Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function were investigated.
Methods
This prospective diagnostic study included patients visiting the ENT Department of our Hospital, between April and June 2021. Patients were grouped into Eustachian tube dysfunction (ETD) and control groups according to tympanometry diagnosis results. The diagnostic value of the T-ETDQ was evaluated using receiver-operating characteristic (ROC) curve analysis.
Results
There were 48 patients with Obstructive ETD and 24 patients without. The area under the ROC curve (AUC) of T-ETDQ was 0.898 (95% confidence interval [CI] 0.826–0.969), and the highest sensitivity and specificity were 76.7% and 86.7% respectively when the positive cutoff value was 4.72. The AUC of Eustachian tube score (ETS) was 0.731 (95% CI 0.625–0.837) and the highest sensitivity and specificity were 48.3% and 90.0% respectively when the positive cut-off value was 4.5. The ETS and T-ETDQ had kappa values of 0.311 and 0.585, respectively (
P
< 0.001 for both), showing both methods were comparable to tympanometry; however, T-ETDQ had more consistent results than ETS.
Conclusion
T-ETDQ can effectively quantify and evaluate ETD severity in adults, has a higher diagnostic value than ETS, making it a suitable diagnostic tool.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34590179</pmid><doi>10.1007/s00405-021-07108-6</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-7755-7945</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0937-4477 |
| ispartof | European archives of oto-rhino-laryngology, 2022-05, Vol.279 (5), p.2223-2230 |
| issn | 0937-4477 1434-4726 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2578151942 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Acoustic Impedance Tests Adult Ear Diseases - diagnosis Eustachian Tube Head and Neck Surgery Humans Medicine Medicine & Public Health Neurosurgery Otorhinolaryngology Prospective Studies Reproducibility of Results Review Article |
| title | Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T20%3A30%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20value%20of%20the%20Eustachian%20Tube%20Function%20Scoring%20System%20T-ETDQ:%20a%20prospective%20diagnostic%20study&rft.jtitle=European%20archives%20of%20oto-rhino-laryngology&rft.au=Lu,%20Hongyi&rft.date=2022-05&rft.volume=279&rft.issue=5&rft.spage=2223&rft.epage=2230&rft.pages=2223-2230&rft.issn=0937-4477&rft.eissn=1434-4726&rft_id=info:doi/10.1007/s00405-021-07108-6&rft_dat=%3Cproquest_cross%3E2578151942%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2578151942&rft_id=info:pmid/34590179&rfr_iscdi=true |