MicroRNAs regulating SOX2 in cancer progression and therapy response

The proliferation, metastasis and therapy response of tumour cells are tightly regulated by interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3′-UTR of mRNA and down-regulate expression of target gene. The miRNAs target various molecular pathways in regulating biologi...

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Veröffentlicht in:	Expert reviews in molecular medicine 2021-09, Vol.23, p.e13-e13, Article e13
Hauptverfasser:	Mirzaei, Sepideh, Saebfar, Hamidreza, Gholami, Mohammad Hossein, Hashemi, Farid, Zarrabi, Ali, Zabolian, Amirhossein, Entezari, Maliheh, Hushmandi, Kiavash, Samarghandian, Saeed, Aref, Amir Reza, Ashrafizadeh, Milad, Khan, Haroon
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Angiogenesis Apoptosis Biomarkers Breast cancer Cancer Cancer therapies Cell cycle Cell proliferation Chemotherapy Colorectal cancer Esophagus Ewings sarcoma Experiments Gene amplification Gene expression Gene Expression Regulation, Neoplastic Genomes Humans Kinases Liver cancer Localization Lung cancer Medical prognosis Metastases Metastasis MicroRNAs MicroRNAs - genetics miRNA Neoplasms - genetics Neoplasms - therapy NF-κB protein Proteins Review RNA, Circular RNA, Long Noncoding Signal transduction SOXB1 Transcription Factors - genetics Stem cells Transcription factors Tumor necrosis factor-α Tumors
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