Standardizing premedication for non-emergent neonatal tracheal intubations improves compliance and patient outcomes
Objective We sought to standardize and improve compliance with evidence-based premedication for non-emergent neonatal intubations in two academic-affiliated Neonatal Intensive Care Units. Study design A multidisciplinary team created guidelines and electronic medical record order sets for intubation...
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Veröffentlicht in: | Journal of perinatology 2022-01, Vol.42 (1), p.132-138 |
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creator | Shay, Rebecca Weikel, Blair W. Grover, Theresa Barry, James S. |
description | Objective
We sought to standardize and improve compliance with evidence-based premedication for non-emergent neonatal intubations in two academic-affiliated Neonatal Intensive Care Units.
Study design
A multidisciplinary team created guidelines and electronic medical record order sets for intubation. Compliance with recommended premedication, number of intubation attempts, and frequency of bradycardia and desaturation were assessed.
Results
387 intubation procedures were reviewed. Provision of recommended premedication increased by 36% and 75% at the level III and IV units, respectively. Decreased frequency of bradycardia during intubation (
p
= 0.0003) occurred in the level III unit. A reduction in number of intubation attempts (
p
≤ 0.001), improvement in first-attempt intubation success (
p
≤ 0.001), and decreased frequency of bradycardia (
p
= 0.01) and desaturation (
p
= 0.02) during intubation occurred in the level IV unit.
Conclusions
This quality improvement initiative improved standardized premedication compliance and decreased adverse events associated with non-emergent neonatal intubations in two separate units. |
doi_str_mv | 10.1038/s41372-021-01215-2 |
format | Article |
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We sought to standardize and improve compliance with evidence-based premedication for non-emergent neonatal intubations in two academic-affiliated Neonatal Intensive Care Units.
Study design
A multidisciplinary team created guidelines and electronic medical record order sets for intubation. Compliance with recommended premedication, number of intubation attempts, and frequency of bradycardia and desaturation were assessed.
Results
387 intubation procedures were reviewed. Provision of recommended premedication increased by 36% and 75% at the level III and IV units, respectively. Decreased frequency of bradycardia during intubation (
p
= 0.0003) occurred in the level III unit. A reduction in number of intubation attempts (
p
≤ 0.001), improvement in first-attempt intubation success (
p
≤ 0.001), and decreased frequency of bradycardia (
p
= 0.01) and desaturation (
p
= 0.02) during intubation occurred in the level IV unit.
Conclusions
This quality improvement initiative improved standardized premedication compliance and decreased adverse events associated with non-emergent neonatal intubations in two separate units.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-021-01215-2</identifier><identifier>PMID: 34584197</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/699/1785 ; 692/700/1720 ; Bradycardia ; Bradycardia - etiology ; Bradycardia - prevention & control ; Cardiac arrhythmia ; Desaturation ; Electronic health records ; Electronic medical records ; Hospitals ; Humans ; Infant, Newborn ; Intensive care units ; Intensive Care Units, Neonatal ; Intubation ; Intubation, Intratracheal - methods ; Medicine ; Medicine & Public Health ; Neonates ; Newborn babies ; Patient compliance ; Pediatric Surgery ; Pediatrics ; Premedication ; Prospective Studies ; Quality control ; Quality Improvement Article</subject><ispartof>Journal of perinatology, 2022-01, Vol.42 (1), p.132-138</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Nature America, Inc.</rights><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-f5fabf319d8669f37ba7443cd23aa8fc869bba46a70a4ed3b5215544f5e41a253</citedby><cites>FETCH-LOGICAL-c375t-f5fabf319d8669f37ba7443cd23aa8fc869bba46a70a4ed3b5215544f5e41a253</cites><orcidid>0000-0002-7181-2757</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41372-021-01215-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/s41372-021-01215-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34584197$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shay, Rebecca</creatorcontrib><creatorcontrib>Weikel, Blair W.</creatorcontrib><creatorcontrib>Grover, Theresa</creatorcontrib><creatorcontrib>Barry, James S.</creatorcontrib><title>Standardizing premedication for non-emergent neonatal tracheal intubations improves compliance and patient outcomes</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><addtitle>J Perinatol</addtitle><description>Objective
We sought to standardize and improve compliance with evidence-based premedication for non-emergent neonatal intubations in two academic-affiliated Neonatal Intensive Care Units.
Study design
A multidisciplinary team created guidelines and electronic medical record order sets for intubation. Compliance with recommended premedication, number of intubation attempts, and frequency of bradycardia and desaturation were assessed.
Results
387 intubation procedures were reviewed. Provision of recommended premedication increased by 36% and 75% at the level III and IV units, respectively. Decreased frequency of bradycardia during intubation (
p
= 0.0003) occurred in the level III unit. A reduction in number of intubation attempts (
p
≤ 0.001), improvement in first-attempt intubation success (
p
≤ 0.001), and decreased frequency of bradycardia (
p
= 0.01) and desaturation (
p
= 0.02) during intubation occurred in the level IV unit.
Conclusions
This quality improvement initiative improved standardized premedication compliance and decreased adverse events associated with non-emergent neonatal intubations in two separate units.</description><subject>692/699/1785</subject><subject>692/700/1720</subject><subject>Bradycardia</subject><subject>Bradycardia - etiology</subject><subject>Bradycardia - prevention & control</subject><subject>Cardiac arrhythmia</subject><subject>Desaturation</subject><subject>Electronic health records</subject><subject>Electronic medical records</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Intensive care units</subject><subject>Intensive Care Units, Neonatal</subject><subject>Intubation</subject><subject>Intubation, Intratracheal - methods</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neonates</subject><subject>Newborn babies</subject><subject>Patient compliance</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Premedication</subject><subject>Prospective Studies</subject><subject>Quality control</subject><subject>Quality Improvement Article</subject><issn>0743-8346</issn><issn>1476-5543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1vFSEUhonR2Gv1D7gwJG7coHwO3KVp_EqauGi7JmcYuNLMwAiMif76cnurJi5cQXif857DeRF6yehbRoV5VyUTmhPKGaGMM0X4I7RjUg9EKSkeox3VUhAj5HCGntV6S-lR1E_RmZDKSLbXO1SvGqQJyhR_xXTAa_GLn6KDFnPCIRecciL9rRx8ajj5nKDBjFsB9833S0xtG-_piuOylvzDV-zyss4RkvO4m-O168fqvLWu-PocPQkwV__i4TxHNx8_XF98JpdfP325eH9JnNCqkaACjEGw_WSGYR-EHkFLKdzEBYAJzgz7cQQ5gKYg_SRG1XegpAzKSwZciXP05uTbx_q--drsEqvz8wz9H1u1XGmtBTWD6ejrf9DbvJXUp7N84Fxo02foFD9RruRaiw92LXGB8tMyao-R2FMktkdi7yOxvBe9erDexr7bPyW_M-iAOAG1S-ngy9_e_7G9A6BGmV0</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Shay, Rebecca</creator><creator>Weikel, Blair W.</creator><creator>Grover, Theresa</creator><creator>Barry, James S.</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7RV</scope><scope>7T5</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7181-2757</orcidid></search><sort><creationdate>20220101</creationdate><title>Standardizing premedication for non-emergent neonatal tracheal intubations improves compliance and patient outcomes</title><author>Shay, Rebecca ; Weikel, Blair W. ; Grover, Theresa ; Barry, James S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-f5fabf319d8669f37ba7443cd23aa8fc869bba46a70a4ed3b5215544f5e41a253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>692/699/1785</topic><topic>692/700/1720</topic><topic>Bradycardia</topic><topic>Bradycardia - etiology</topic><topic>Bradycardia - prevention & control</topic><topic>Cardiac arrhythmia</topic><topic>Desaturation</topic><topic>Electronic health records</topic><topic>Electronic medical records</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Intensive care units</topic><topic>Intensive Care Units, Neonatal</topic><topic>Intubation</topic><topic>Intubation, Intratracheal - methods</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neonates</topic><topic>Newborn babies</topic><topic>Patient compliance</topic><topic>Pediatric Surgery</topic><topic>Pediatrics</topic><topic>Premedication</topic><topic>Prospective Studies</topic><topic>Quality control</topic><topic>Quality Improvement Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shay, Rebecca</creatorcontrib><creatorcontrib>Weikel, Blair W.</creatorcontrib><creatorcontrib>Grover, Theresa</creatorcontrib><creatorcontrib>Barry, James S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shay, Rebecca</au><au>Weikel, Blair W.</au><au>Grover, Theresa</au><au>Barry, James S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Standardizing premedication for non-emergent neonatal tracheal intubations improves compliance and patient outcomes</atitle><jtitle>Journal of perinatology</jtitle><stitle>J Perinatol</stitle><addtitle>J Perinatol</addtitle><date>2022-01-01</date><risdate>2022</risdate><volume>42</volume><issue>1</issue><spage>132</spage><epage>138</epage><pages>132-138</pages><issn>0743-8346</issn><eissn>1476-5543</eissn><abstract>Objective
We sought to standardize and improve compliance with evidence-based premedication for non-emergent neonatal intubations in two academic-affiliated Neonatal Intensive Care Units.
Study design
A multidisciplinary team created guidelines and electronic medical record order sets for intubation. Compliance with recommended premedication, number of intubation attempts, and frequency of bradycardia and desaturation were assessed.
Results
387 intubation procedures were reviewed. Provision of recommended premedication increased by 36% and 75% at the level III and IV units, respectively. Decreased frequency of bradycardia during intubation (
p
= 0.0003) occurred in the level III unit. A reduction in number of intubation attempts (
p
≤ 0.001), improvement in first-attempt intubation success (
p
≤ 0.001), and decreased frequency of bradycardia (
p
= 0.01) and desaturation (
p
= 0.02) during intubation occurred in the level IV unit.
Conclusions
This quality improvement initiative improved standardized premedication compliance and decreased adverse events associated with non-emergent neonatal intubations in two separate units.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>34584197</pmid><doi>10.1038/s41372-021-01215-2</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7181-2757</orcidid></addata></record> |
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issn | 0743-8346 1476-5543 |
language | eng |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | 692/699/1785 692/700/1720 Bradycardia Bradycardia - etiology Bradycardia - prevention & control Cardiac arrhythmia Desaturation Electronic health records Electronic medical records Hospitals Humans Infant, Newborn Intensive care units Intensive Care Units, Neonatal Intubation Intubation, Intratracheal - methods Medicine Medicine & Public Health Neonates Newborn babies Patient compliance Pediatric Surgery Pediatrics Premedication Prospective Studies Quality control Quality Improvement Article |
title | Standardizing premedication for non-emergent neonatal tracheal intubations improves compliance and patient outcomes |
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