Clinical efficacy and safety of different doses of intrathecal methotrexate in the treatment of leptomeningeal carcinomatosis: a prospective and single-arm study

Abstract Objective To investigate the clinical efficacy and safety of different doses of intrathecal methotrexate in the treatment of leptomeningeal carcinomatosis. Methods 53 patients admitted to the Second Hospital of Hebei Medical University with leptomeningeal carcinomatosis were recruited. They...

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Veröffentlicht in:	Japanese journal of clinical oncology 2021-12, Vol.51 (12), p.1715-1722
Hauptverfasser:	Hou, Lan, Han, Weixin, Jin, Jie, Chen, Xin, Zou, Yueli, Yan, Litian, He, Junying, Bu, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Injections, Spinal Meningeal Carcinomatosis - drug therapy Methotrexate - adverse effects Prospective Studies Treatment Outcome
Online-Zugang:	Volltext
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