Outcome of Impella 2.5 use in patients undergoing Percutaneous Coronary Intervention in Henan, China: a case series

Background: Acute myocardial infarction (AMI) complicated by cardiogenic shock (AMI-CS) or heart failure is associated with an unacceptably high in-hospital mortality of 33%–55% and a lost chance to accept PCI (Percutaneous Coronary Intervention). Aim: The aim of the study was to find out whether pe...

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Veröffentlicht in:Perfusion 2023-01, Vol.38 (1), p.208-213
Hauptverfasser: Bhat, Rafiq Ahmed, Ali, Syed Manzoor, Rathi, Akanksha, Bhat, Javaid Akhter, Iqbal, Raja Saqib, Islam, Md Monowarul, Maqbool, Syed, Tibrewal, Abhishek, Qu, Yongsheng, Zhang, You, Sun, Yuxiao, Xiao, Wentao, Gao, Chuanyu
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container_end_page 213
container_issue 1
container_start_page 208
container_title Perfusion
container_volume 38
creator Bhat, Rafiq Ahmed
Ali, Syed Manzoor
Rathi, Akanksha
Bhat, Javaid Akhter
Iqbal, Raja Saqib
Islam, Md Monowarul
Maqbool, Syed
Tibrewal, Abhishek
Qu, Yongsheng
Zhang, You
Sun, Yuxiao
Xiao, Wentao
Gao, Chuanyu
description Background: Acute myocardial infarction (AMI) complicated by cardiogenic shock (AMI-CS) or heart failure is associated with an unacceptably high in-hospital mortality of 33%–55% and a lost chance to accept PCI (Percutaneous Coronary Intervention). Aim: The aim of the study was to find out whether percutaneous hemodynamic support device Impella 2.5 improves prognosis of high-risk PCI patients or not. Methods: This study was a case series involving six patients who underwent a Left Ventricular Assist Device (LVAD, Impella 2.5, Abiomed, Danvers, MA) implantation after suffering from AMI with a very low ejection fraction and acute heart failure. The clinical experience and outcomes of the patients are hereby discussed. Results: All PCI procedures were safely completed under LVAD support. The hemodynamic parameters of all patients improved clinically over the next 30 days and following 12 months after Impella insertion except in two patients, of which one patient (Case number 6) died 4 days post-Impella protected PCI procedure due to acute left ventricle heart failure with cardiogenic shock and pulmonary oedema; and another one died at 12 months after Impella protected PCI procedure (Case number 4) due to decompensated heart failure and infected pneumonia. Conclusion: Percutaneous hemodynamic support is favorable and feasible during high risk Percutaneous Coronary Intervention (PCI). A bigger study is needed to substantiate the claims of the current study.
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Aim: The aim of the study was to find out whether percutaneous hemodynamic support device Impella 2.5 improves prognosis of high-risk PCI patients or not. Methods: This study was a case series involving six patients who underwent a Left Ventricular Assist Device (LVAD, Impella 2.5, Abiomed, Danvers, MA) implantation after suffering from AMI with a very low ejection fraction and acute heart failure. The clinical experience and outcomes of the patients are hereby discussed. Results: All PCI procedures were safely completed under LVAD support. The hemodynamic parameters of all patients improved clinically over the next 30 days and following 12 months after Impella insertion except in two patients, of which one patient (Case number 6) died 4 days post-Impella protected PCI procedure due to acute left ventricle heart failure with cardiogenic shock and pulmonary oedema; and another one died at 12 months after Impella protected PCI procedure (Case number 4) due to decompensated heart failure and infected pneumonia. Conclusion: Percutaneous hemodynamic support is favorable and feasible during high risk Percutaneous Coronary Intervention (PCI). A bigger study is needed to substantiate the claims of the current study.</description><identifier>ISSN: 0267-6591</identifier><identifier>EISSN: 1477-111X</identifier><identifier>DOI: 10.1177/02676591211049018</identifier><identifier>PMID: 34581607</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Angioplasty ; Congestive heart failure ; Edema ; Heart failure ; Heart Failure - complications ; Heart Failure - surgery ; Heart-Assist Devices - adverse effects ; Hemodynamics ; Humans ; Myocardial infarction ; Myocardial Infarction - etiology ; Patients ; Percutaneous Coronary Intervention - adverse effects ; Retrospective Studies ; Shock, Cardiogenic - complications ; Shock, Cardiogenic - surgery ; Stents ; Treatment Outcome ; Ventricle ; Ventricular assist devices</subject><ispartof>Perfusion, 2023-01, Vol.38 (1), p.208-213</ispartof><rights>The Author(s) 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c320t-e9bf24c9360d2ca0ca7b06f72811aa20c52cdd479f0994cf35b5e06da67158133</cites><orcidid>0000-0001-7079-2283 ; 0000-0003-1149-7190</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/02676591211049018$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/02676591211049018$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34581607$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bhat, Rafiq Ahmed</creatorcontrib><creatorcontrib>Ali, Syed Manzoor</creatorcontrib><creatorcontrib>Rathi, Akanksha</creatorcontrib><creatorcontrib>Bhat, Javaid Akhter</creatorcontrib><creatorcontrib>Iqbal, Raja Saqib</creatorcontrib><creatorcontrib>Islam, Md Monowarul</creatorcontrib><creatorcontrib>Maqbool, Syed</creatorcontrib><creatorcontrib>Tibrewal, Abhishek</creatorcontrib><creatorcontrib>Qu, Yongsheng</creatorcontrib><creatorcontrib>Zhang, You</creatorcontrib><creatorcontrib>Sun, Yuxiao</creatorcontrib><creatorcontrib>Xiao, Wentao</creatorcontrib><creatorcontrib>Gao, Chuanyu</creatorcontrib><title>Outcome of Impella 2.5 use in patients undergoing Percutaneous Coronary Intervention in Henan, China: a case series</title><title>Perfusion</title><addtitle>Perfusion</addtitle><description>Background: Acute myocardial infarction (AMI) complicated by cardiogenic shock (AMI-CS) or heart failure is associated with an unacceptably high in-hospital mortality of 33%–55% and a lost chance to accept PCI (Percutaneous Coronary Intervention). Aim: The aim of the study was to find out whether percutaneous hemodynamic support device Impella 2.5 improves prognosis of high-risk PCI patients or not. Methods: This study was a case series involving six patients who underwent a Left Ventricular Assist Device (LVAD, Impella 2.5, Abiomed, Danvers, MA) implantation after suffering from AMI with a very low ejection fraction and acute heart failure. The clinical experience and outcomes of the patients are hereby discussed. Results: All PCI procedures were safely completed under LVAD support. The hemodynamic parameters of all patients improved clinically over the next 30 days and following 12 months after Impella insertion except in two patients, of which one patient (Case number 6) died 4 days post-Impella protected PCI procedure due to acute left ventricle heart failure with cardiogenic shock and pulmonary oedema; and another one died at 12 months after Impella protected PCI procedure (Case number 4) due to decompensated heart failure and infected pneumonia. Conclusion: Percutaneous hemodynamic support is favorable and feasible during high risk Percutaneous Coronary Intervention (PCI). 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The hemodynamic parameters of all patients improved clinically over the next 30 days and following 12 months after Impella insertion except in two patients, of which one patient (Case number 6) died 4 days post-Impella protected PCI procedure due to acute left ventricle heart failure with cardiogenic shock and pulmonary oedema; and another one died at 12 months after Impella protected PCI procedure (Case number 4) due to decompensated heart failure and infected pneumonia. Conclusion: Percutaneous hemodynamic support is favorable and feasible during high risk Percutaneous Coronary Intervention (PCI). A bigger study is needed to substantiate the claims of the current study.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>34581607</pmid><doi>10.1177/02676591211049018</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-7079-2283</orcidid><orcidid>https://orcid.org/0000-0003-1149-7190</orcidid></addata></record>
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subjects Angioplasty
Congestive heart failure
Edema
Heart failure
Heart Failure - complications
Heart Failure - surgery
Heart-Assist Devices - adverse effects
Hemodynamics
Humans
Myocardial infarction
Myocardial Infarction - etiology
Patients
Percutaneous Coronary Intervention - adverse effects
Retrospective Studies
Shock, Cardiogenic - complications
Shock, Cardiogenic - surgery
Stents
Treatment Outcome
Ventricle
Ventricular assist devices
title Outcome of Impella 2.5 use in patients undergoing Percutaneous Coronary Intervention in Henan, China: a case series
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