Inhibitory effect of Pyr6 (an Orai channel blocker) on agonist‐induced contractions in rat uterus

Aim Both human and rat myometrium express stromal interaction molecule (STIM) and Orai/transient receptor potential canonical (TRPC) proteins, which are components of plasma membrane Ca2+ store‐operated channels. There are reports that these proteins mediate agonist‐induced Ca2+ influx in cultured m...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2021-12, Vol.47 (12), p.4306-4318
Hauptverfasser:	de Sousa, Ícaro Araújo, de Meneses, Gabriel Medina Sobreira, Cardoso, José Victor Miranda, Lopes, Pablo Queiroz, de Sousa, Joubert Aires, Cavalcanti, Suzana Maria Pereira Galvão, da Silva Cavalcanti, Paulo Marques, Filho, Francisco Chagas
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Animals Calcium channels Calcium influx Carbachol Cyclopiazonic acid Female Myometrium Orai channels Oxytocin Pregnancy Pyr6 rat uterus Rats Transient receptor potential proteins TRPC channels Uterine Contraction uterine contractions Uterus
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