Thiol/disulfide homeostasis and its relationship with insulin resistance in patients with rosacea

Background Rosacea is a chronic inflammatory cutaneous disease that can be associated with cardiometabolic disorders. Oxidative stress is included in the pathogenesis of rosacea, and thiol‐disulfide homeostasis (TDH) acts as antioxidants. Objective To evaluate the TDH and metabolic parameters in patients with rosacea. Material and Methods A total of 42 rosacea patients and 50 controls participated in this prospective study. Demographic data, clinical entities, anthropometric measurements, and laboratory findings were recorded. Additionally, TDH was measured by an automated spectrophotometric method. Results Rosacea patients had greater body mass index values (27.9 ± 5.2 kg/m² vs. 23 ± 1.4 kg/m², p