Dynein- and kinesin- mediated intracellular transport on microtubules facilitates RABV infection

•The polymerization of microtubules is required for RABV infection in N2a cells.•The functional disruption of the cytoplasmic dynein inhibited RABV infection.•Blockage in kinesin-based motility attenuated RABV infection. Rabies, caused by rabies virus (RABV), is one of the most important neurotropic...

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Veröffentlicht in:	Veterinary microbiology 2021-11, Vol.262, p.109241-109241, Article 109241
Hauptverfasser:	Xu, Jing, Gao, Jie, Zhang, Maolin, Zhang, Danwei, Duan, Ming, Guan, Zhenhong, Guo, Yidi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Colchicine Dynein Dyneins - metabolism Infections Kinesin Kinesins - metabolism Lyssavirus Microtubules Microtubules - metabolism Rabies Rabies - veterinary Rabies - virology Rabies virus - drug effects RABV Trafficking Transfection
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