A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy
Purpose Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML p...
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| Veröffentlicht in: | Supportive care in cancer 2022-02, Vol.30 (2), p.1673-1679 |
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| creator | McKeown, Christi Ricciuti, Asha Agha, Mounzer Raptis, Anastasios Hou, Jing-Zhou Farah, Rafic Redner, Robert L. Im, Annie Dorritie, Kathleen A. Sehgal, Alison Rossetti, James Lontos, Konstantinos Bovbjerg, Dana H. Normolle, Daniel Boyiadzis, Michael |
| description | Purpose
Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited.
Methods
We conducted a prospective observational study and evaluated the complications associated with the use of CVCs in adult AML patients during induction chemotherapy and evaluated quality of life outcomes as reported by the patients during and after their hospitalization.
Results
Fifty newly diagnosed patients with AML (median age, 59 years) who received intensive induction chemotherapy were enrolled in the study. Twenty-nine patients (58%) had a peripherally inserted central catheters (PICCs) placed and 21 (42%) patients received a Hickmann tunneled central catheter (TCC). Three percent of cases developed catheter-related thrombosis in PICCs and no thrombosis in TCCs. Catheter-related bloodstream infection was diagnosed in 8% of patients. CVC occlusion occurred in 44 patients (88%). The total number of occlusion events was 128; 97% of patients with PICCs and 76% of patients with TCCs (
p
= 0.003). All patients reported that the use of CVC simplified their course of treatment. Most patients reported similar restrictions in activity associated with TCCs and PICCs.
Conclusion
The present study demonstrates that thrombosis and catheter-related bloodstream infections remain important complications of CVCs in AML patients. Occlusion rates were higher with the use of PICCs and the use of CVCs impacted the quality of life. |
| doi_str_mv | 10.1007/s00520-021-06339-x |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2576655913</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A688731727</galeid><sourcerecordid>A688731727</sourcerecordid><originalsourceid>FETCH-LOGICAL-c403t-3d48a56a5571043b5a4dedcf84ccbaa18c44ecb0dcfb4ab7c71cadd9703dd9433</originalsourceid><addsrcrecordid>eNp9kctu1DAUhi1ERYfCC7BAltiwCbXjW7IcVeUiVWJT1pZjn8y4JE6wnbZ5EZ4XD9MCYtGNb-fz7-P_R-gNJR8oIeo8ESJqUpGaVkQy1lb3z9CGcsYqVXbP0Ya0nFacCXGKXqZ0QwhVStQv0CnjQtZUNhv0c4vnOKUZbPa3gFNe3IqnHuc94CXBYWkh5GgGfAthWhK2ptQyxIR9wLPJvpQTDnA3rNh5swtTAofvfN5jY5cMeFxhmLzDAyzfYfQG5wgmPzI-uKW8PQVs9zBORTuaeX2FTnozJHj9MJ-hbx8vry8-V1dfP3252F5VlhOWK-Z4Y4Q0QihKOOuE4Q6c7RtubWcMbSznYDtSjjpuOmUVtca5VhFWxuLUGXp_1C0m_FggZT36ZGEYTIDyWV0LJaUQLT2g7_5Db6YlhtKdriWVXIlW_kPtzADah34q3tmDqN7KplGMqloVqj5StnifIvR6jn40cdWU6EO2-pitLtnq39nq-3Lp7UMDSzeC-3PlMcwCsCOQSinsIP7t8AnZXzn_swU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2616475963</pqid></control><display><type>article</type><title>A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>McKeown, Christi ; Ricciuti, Asha ; Agha, Mounzer ; Raptis, Anastasios ; Hou, Jing-Zhou ; Farah, Rafic ; Redner, Robert L. ; Im, Annie ; Dorritie, Kathleen A. ; Sehgal, Alison ; Rossetti, James ; Lontos, Konstantinos ; Bovbjerg, Dana H. ; Normolle, Daniel ; Boyiadzis, Michael</creator><creatorcontrib>McKeown, Christi ; Ricciuti, Asha ; Agha, Mounzer ; Raptis, Anastasios ; Hou, Jing-Zhou ; Farah, Rafic ; Redner, Robert L. ; Im, Annie ; Dorritie, Kathleen A. ; Sehgal, Alison ; Rossetti, James ; Lontos, Konstantinos ; Bovbjerg, Dana H. ; Normolle, Daniel ; Boyiadzis, Michael</creatorcontrib><description>Purpose
Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited.
Methods
We conducted a prospective observational study and evaluated the complications associated with the use of CVCs in adult AML patients during induction chemotherapy and evaluated quality of life outcomes as reported by the patients during and after their hospitalization.
Results
Fifty newly diagnosed patients with AML (median age, 59 years) who received intensive induction chemotherapy were enrolled in the study. Twenty-nine patients (58%) had a peripherally inserted central catheters (PICCs) placed and 21 (42%) patients received a Hickmann tunneled central catheter (TCC). Three percent of cases developed catheter-related thrombosis in PICCs and no thrombosis in TCCs. Catheter-related bloodstream infection was diagnosed in 8% of patients. CVC occlusion occurred in 44 patients (88%). The total number of occlusion events was 128; 97% of patients with PICCs and 76% of patients with TCCs (
p
= 0.003). All patients reported that the use of CVC simplified their course of treatment. Most patients reported similar restrictions in activity associated with TCCs and PICCs.
Conclusion
The present study demonstrates that thrombosis and catheter-related bloodstream infections remain important complications of CVCs in AML patients. Occlusion rates were higher with the use of PICCs and the use of CVCs impacted the quality of life.</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-021-06339-x</identifier><identifier>PMID: 34562168</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Antimitotic agents ; Antineoplastic agents ; Cancer ; Catheter-Related Infections - epidemiology ; Catheterization, Central Venous - adverse effects ; Catheterization, Peripheral - adverse effects ; Catheters ; Central Venous Catheters - adverse effects ; Chemotherapy ; Health aspects ; Humans ; Induction Chemotherapy ; Leukemia ; Leukemia, Myeloid, Acute - drug therapy ; Medical diagnosis ; Medicine ; Medicine & Public Health ; Middle Aged ; Mortality ; Nursing ; Nursing Research ; Oncology ; Oncology, Experimental ; Original Article ; Pain Medicine ; Palliative care ; Prospective Studies ; Quality of Life ; Rehabilitation Medicine ; Risk Factors ; Thrombosis</subject><ispartof>Supportive care in cancer, 2022-02, Vol.30 (2), p.1673-1679</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>COPYRIGHT 2022 Springer</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-3d48a56a5571043b5a4dedcf84ccbaa18c44ecb0dcfb4ab7c71cadd9703dd9433</citedby><cites>FETCH-LOGICAL-c403t-3d48a56a5571043b5a4dedcf84ccbaa18c44ecb0dcfb4ab7c71cadd9703dd9433</cites><orcidid>0000-0001-6699-6355</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-021-06339-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-021-06339-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34562168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McKeown, Christi</creatorcontrib><creatorcontrib>Ricciuti, Asha</creatorcontrib><creatorcontrib>Agha, Mounzer</creatorcontrib><creatorcontrib>Raptis, Anastasios</creatorcontrib><creatorcontrib>Hou, Jing-Zhou</creatorcontrib><creatorcontrib>Farah, Rafic</creatorcontrib><creatorcontrib>Redner, Robert L.</creatorcontrib><creatorcontrib>Im, Annie</creatorcontrib><creatorcontrib>Dorritie, Kathleen A.</creatorcontrib><creatorcontrib>Sehgal, Alison</creatorcontrib><creatorcontrib>Rossetti, James</creatorcontrib><creatorcontrib>Lontos, Konstantinos</creatorcontrib><creatorcontrib>Bovbjerg, Dana H.</creatorcontrib><creatorcontrib>Normolle, Daniel</creatorcontrib><creatorcontrib>Boyiadzis, Michael</creatorcontrib><title>A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description>Purpose
Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited.
Methods
We conducted a prospective observational study and evaluated the complications associated with the use of CVCs in adult AML patients during induction chemotherapy and evaluated quality of life outcomes as reported by the patients during and after their hospitalization.
Results
Fifty newly diagnosed patients with AML (median age, 59 years) who received intensive induction chemotherapy were enrolled in the study. Twenty-nine patients (58%) had a peripherally inserted central catheters (PICCs) placed and 21 (42%) patients received a Hickmann tunneled central catheter (TCC). Three percent of cases developed catheter-related thrombosis in PICCs and no thrombosis in TCCs. Catheter-related bloodstream infection was diagnosed in 8% of patients. CVC occlusion occurred in 44 patients (88%). The total number of occlusion events was 128; 97% of patients with PICCs and 76% of patients with TCCs (
p
= 0.003). All patients reported that the use of CVC simplified their course of treatment. Most patients reported similar restrictions in activity associated with TCCs and PICCs.
Conclusion
The present study demonstrates that thrombosis and catheter-related bloodstream infections remain important complications of CVCs in AML patients. Occlusion rates were higher with the use of PICCs and the use of CVCs impacted the quality of life.</description><subject>Adult</subject><subject>Antimitotic agents</subject><subject>Antineoplastic agents</subject><subject>Cancer</subject><subject>Catheter-Related Infections - epidemiology</subject><subject>Catheterization, Central Venous - adverse effects</subject><subject>Catheterization, Peripheral - adverse effects</subject><subject>Catheters</subject><subject>Central Venous Catheters - adverse effects</subject><subject>Chemotherapy</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Induction Chemotherapy</subject><subject>Leukemia</subject><subject>Leukemia, Myeloid, Acute - drug therapy</subject><subject>Medical diagnosis</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Nursing</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Oncology, Experimental</subject><subject>Original Article</subject><subject>Pain Medicine</subject><subject>Palliative care</subject><subject>Prospective Studies</subject><subject>Quality of Life</subject><subject>Rehabilitation Medicine</subject><subject>Risk Factors</subject><subject>Thrombosis</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kctu1DAUhi1ERYfCC7BAltiwCbXjW7IcVeUiVWJT1pZjn8y4JE6wnbZ5EZ4XD9MCYtGNb-fz7-P_R-gNJR8oIeo8ESJqUpGaVkQy1lb3z9CGcsYqVXbP0Ya0nFacCXGKXqZ0QwhVStQv0CnjQtZUNhv0c4vnOKUZbPa3gFNe3IqnHuc94CXBYWkh5GgGfAthWhK2ptQyxIR9wLPJvpQTDnA3rNh5swtTAofvfN5jY5cMeFxhmLzDAyzfYfQG5wgmPzI-uKW8PQVs9zBORTuaeX2FTnozJHj9MJ-hbx8vry8-V1dfP3252F5VlhOWK-Z4Y4Q0QihKOOuE4Q6c7RtubWcMbSznYDtSjjpuOmUVtca5VhFWxuLUGXp_1C0m_FggZT36ZGEYTIDyWV0LJaUQLT2g7_5Db6YlhtKdriWVXIlW_kPtzADah34q3tmDqN7KplGMqloVqj5StnifIvR6jn40cdWU6EO2-pitLtnq39nq-3Lp7UMDSzeC-3PlMcwCsCOQSinsIP7t8AnZXzn_swU</recordid><startdate>20220201</startdate><enddate>20220201</enddate><creator>McKeown, Christi</creator><creator>Ricciuti, Asha</creator><creator>Agha, Mounzer</creator><creator>Raptis, Anastasios</creator><creator>Hou, Jing-Zhou</creator><creator>Farah, Rafic</creator><creator>Redner, Robert L.</creator><creator>Im, Annie</creator><creator>Dorritie, Kathleen A.</creator><creator>Sehgal, Alison</creator><creator>Rossetti, James</creator><creator>Lontos, Konstantinos</creator><creator>Bovbjerg, Dana H.</creator><creator>Normolle, Daniel</creator><creator>Boyiadzis, Michael</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>POGQB</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PRQQA</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6699-6355</orcidid></search><sort><creationdate>20220201</creationdate><title>A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy</title><author>McKeown, Christi ; Ricciuti, Asha ; Agha, Mounzer ; Raptis, Anastasios ; Hou, Jing-Zhou ; Farah, Rafic ; Redner, Robert L. ; Im, Annie ; Dorritie, Kathleen A. ; Sehgal, Alison ; Rossetti, James ; Lontos, Konstantinos ; Bovbjerg, Dana H. ; Normolle, Daniel ; Boyiadzis, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-3d48a56a5571043b5a4dedcf84ccbaa18c44ecb0dcfb4ab7c71cadd9703dd9433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adult</topic><topic>Antimitotic agents</topic><topic>Antineoplastic agents</topic><topic>Cancer</topic><topic>Catheter-Related Infections - epidemiology</topic><topic>Catheterization, Central Venous - adverse effects</topic><topic>Catheterization, Peripheral - adverse effects</topic><topic>Catheters</topic><topic>Central Venous Catheters - adverse effects</topic><topic>Chemotherapy</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Induction Chemotherapy</topic><topic>Leukemia</topic><topic>Leukemia, Myeloid, Acute - drug therapy</topic><topic>Medical diagnosis</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Nursing</topic><topic>Nursing Research</topic><topic>Oncology</topic><topic>Oncology, Experimental</topic><topic>Original Article</topic><topic>Pain Medicine</topic><topic>Palliative care</topic><topic>Prospective Studies</topic><topic>Quality of Life</topic><topic>Rehabilitation Medicine</topic><topic>Risk Factors</topic><topic>Thrombosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McKeown, Christi</creatorcontrib><creatorcontrib>Ricciuti, Asha</creatorcontrib><creatorcontrib>Agha, Mounzer</creatorcontrib><creatorcontrib>Raptis, Anastasios</creatorcontrib><creatorcontrib>Hou, Jing-Zhou</creatorcontrib><creatorcontrib>Farah, Rafic</creatorcontrib><creatorcontrib>Redner, Robert L.</creatorcontrib><creatorcontrib>Im, Annie</creatorcontrib><creatorcontrib>Dorritie, Kathleen A.</creatorcontrib><creatorcontrib>Sehgal, Alison</creatorcontrib><creatorcontrib>Rossetti, James</creatorcontrib><creatorcontrib>Lontos, Konstantinos</creatorcontrib><creatorcontrib>Bovbjerg, Dana H.</creatorcontrib><creatorcontrib>Normolle, Daniel</creatorcontrib><creatorcontrib>Boyiadzis, Michael</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest Sociology & Social Sciences Collection</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Social Sciences</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Supportive care in cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McKeown, Christi</au><au>Ricciuti, Asha</au><au>Agha, Mounzer</au><au>Raptis, Anastasios</au><au>Hou, Jing-Zhou</au><au>Farah, Rafic</au><au>Redner, Robert L.</au><au>Im, Annie</au><au>Dorritie, Kathleen A.</au><au>Sehgal, Alison</au><au>Rossetti, James</au><au>Lontos, Konstantinos</au><au>Bovbjerg, Dana H.</au><au>Normolle, Daniel</au><au>Boyiadzis, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy</atitle><jtitle>Supportive care in cancer</jtitle><stitle>Support Care Cancer</stitle><addtitle>Support Care Cancer</addtitle><date>2022-02-01</date><risdate>2022</risdate><volume>30</volume><issue>2</issue><spage>1673</spage><epage>1679</epage><pages>1673-1679</pages><issn>0941-4355</issn><eissn>1433-7339</eissn><abstract>Purpose
Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited.
Methods
We conducted a prospective observational study and evaluated the complications associated with the use of CVCs in adult AML patients during induction chemotherapy and evaluated quality of life outcomes as reported by the patients during and after their hospitalization.
Results
Fifty newly diagnosed patients with AML (median age, 59 years) who received intensive induction chemotherapy were enrolled in the study. Twenty-nine patients (58%) had a peripherally inserted central catheters (PICCs) placed and 21 (42%) patients received a Hickmann tunneled central catheter (TCC). Three percent of cases developed catheter-related thrombosis in PICCs and no thrombosis in TCCs. Catheter-related bloodstream infection was diagnosed in 8% of patients. CVC occlusion occurred in 44 patients (88%). The total number of occlusion events was 128; 97% of patients with PICCs and 76% of patients with TCCs (
p
= 0.003). All patients reported that the use of CVC simplified their course of treatment. Most patients reported similar restrictions in activity associated with TCCs and PICCs.
Conclusion
The present study demonstrates that thrombosis and catheter-related bloodstream infections remain important complications of CVCs in AML patients. Occlusion rates were higher with the use of PICCs and the use of CVCs impacted the quality of life.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34562168</pmid><doi>10.1007/s00520-021-06339-x</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-6699-6355</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0941-4355 |
| ispartof | Supportive care in cancer, 2022-02, Vol.30 (2), p.1673-1679 |
| issn | 0941-4355 1433-7339 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Antimitotic agents Antineoplastic agents Cancer Catheter-Related Infections - epidemiology Catheterization, Central Venous - adverse effects Catheterization, Peripheral - adverse effects Catheters Central Venous Catheters - adverse effects Chemotherapy Health aspects Humans Induction Chemotherapy Leukemia Leukemia, Myeloid, Acute - drug therapy Medical diagnosis Medicine Medicine & Public Health Middle Aged Mortality Nursing Nursing Research Oncology Oncology, Experimental Original Article Pain Medicine Palliative care Prospective Studies Quality of Life Rehabilitation Medicine Risk Factors Thrombosis |
| title | A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy |
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