Updates on sphingolipids: Spotlight on retinopathy

The sphingolipids ceramide (Cer), ceramide-1-phosphate (C1P), sphingosine (Sph), and sphingosine-1-phosphate (S1P)) are key signaling molecules that regulate many patho-biological processes. During the last decade, they have gained increasing attention since they may participate in important and num...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2021-11, Vol.143, p.112197-112197, Article 112197
Hauptverfasser:	Shiwani, Haaris A., Elfaki, Mohammed Y., Memon, Danyal, Ali, Suhayb, Aziz, Abdul, Egom, Emmanuel E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age-related macular degeneration Animals Ceramide Ceramide-1-phosphate Ceramides - metabolism Fingolimod Hydrochloride - therapeutic use Humans Lysophospholipids - metabolism Molecular Targeted Therapy Photoreceptor Photoreceptor Cells, Vertebrate - metabolism Retina - drug effects Retina - metabolism Retina - pathology Retinal Diseases - drug therapy Retinal Diseases - metabolism Retinal Diseases - pathology Retinal Ganglion Cells - metabolism Retinal pigment epithelium Retinal Pigment Epithelium - metabolism Signal Transduction Sphingolipids - metabolism Sphingosine Sphingosine - analogs & derivatives Sphingosine - metabolism Sphingosine 1 Phosphate Receptor Modulators - therapeutic use Sphingosine-1-phosphate Sphingosine-1-Phosphate Receptors - drug effects Sphingosine-1-Phosphate Receptors - metabolism
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