Cross talk: trafficking and functional impact of maternal exosomes at the feto-maternal interface under normal and pathologic states

Fetal cell-derived exosomes promote inflammation in uterine and cervical cells to promote labor and delivery. However, the effect of maternal exosomes on fetal cells is still not known. We tested the hypothesis that cervical cells exposed to infectious and oxidative stress (OS) signals produce exoso...

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Veröffentlicht in:	Biology of reproduction 2021-12, Vol.105 (6), p.1562-1576
Hauptverfasser:	Tantengco, Ourlad Alzeus G, Radnaa, Enkhtuya, Shahin, Hend, Kechichian, Talar, Menon, Ramkumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnion Cell culture Cells, Cultured Cervix Cervix Uteri - immunology Cervix Uteri - metabolism Chorion Decidua Decidua - immunology Decidua - metabolism Enzyme-linked immunosorbent assay Epithelial cells Epithelial Cells - immunology Epithelial Cells - metabolism Exosomes Exosomes - immunology Exosomes - metabolism Extraembryonic Membranes - immunology Extraembryonic Membranes - metabolism Female fetal membrane Fetuses Fluorescence microscopy Health aspects Humans Infection Inflammation Inflammation - metabolism Interleukin 6 Interleukin 8 Lipopolysaccharides Mesenchyme Oxidative Stress paracrine signaling parturition placenta Pregnancy Progesterone Proteins RESEARCH ARTICLE Stem cells Stromal cells Uterus
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