Biomimetic crosslinking of collagen gels by energetic electrons: The role of L-lysine

Energetic electrons have recently evolved as a powerful tool for crosslinking bio-derived hydrogels without the need for adding potentially hazardous reagents. Application of this approach allows for synthesis of biomimetic collagen-derived networks of highly tunable properties and functionalization...

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Veröffentlicht in:	Acta biomaterialia 2022-03, Vol.140, p.219-232
Hauptverfasser:	Wilharm, Nils, Bertmer, Marko, Knolle, Wolfgang, Griebel, Jan, Elsner, Christian, Mayr, Stefan G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption spectroscopy Amino acids Aqueous solutions Biocompatibility Biomaterials Biomedical materials Biomimetic crosslinking Biomimetics Catalysis Chemical bonds Collagen Collagen - chemistry Covalent bonds Cross-Linking Reagents - chemistry Crosslinking Elastin Electron beam processing Electrons Fibers Free radicals Gels Glycine Hydrogels Hydrogels - chemistry Hydroxyl radicals Ionization Lysine Lysyl oxidase Mass spectrometry Mass spectroscopy NMR Nuclear magnetic resonance Polymers Pulse radiolysis Radiation chemistry Reaction kinetics Reagents
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