Injectable Biocatalytic Nanocomposite Hydrogel Factories for Focal Enzyme-Prodrug Cancer Therapy

Systemic enzyme-prodrug therapy (EPT) using nanofactories, nanoparticles encapsulating prodrug-activating enzymes, is a promising concept for anticancer therapy. However, systemic delivery systems can be problematic. As nanofactories are typically carried by the blood circulation to tissues througho...

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Veröffentlicht in:Biomacromolecules 2021-10, Vol.22 (10), p.4217-4227
Hauptverfasser: Ono, Kimika, Hashimoto, Hiroyuki, Katayama, Tokitaka, Ueda, Natsumi, Nagahama, Koji
Format: Artikel
Sprache:eng
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