SNAI1-mediated transcriptional regulation of epithelial-to-mesenchymal transition genes in breast cancer stem cells

Triple-negative breast cancer (TNBC) tumors are composed of a heterogeneous population containing both cancer cells and cancer stem cells (CSCs). These CSCs are generated through an epithelial-to-mesenchymal transition (EMT), thus making it pertinent to identify the unique EMT-molecular targets that...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cellular signalling 2021-11, Vol.87, p.110151-110151, Article 110151
Hauptverfasser:	Singh, Digvijay, Deshmukh, Rohit K., Das, Amitava
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer stem cells Cell Line, Tumor Cell Movement - genetics EMT-associated differential expressed genes Epithelial-Mesenchymal Transition - genetics Epithelial-to-mesenchymal transition Gene Expression Regulation, Neoplastic GM6001 (Ilomastat) Humans Neoplastic Stem Cells - metabolism SNAI1 Snail Family Transcription Factors - genetics Snail Family Transcription Factors - metabolism Triple Negative Breast Neoplasms - genetics Triple Negative Breast Neoplasms - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!