Potential predictors for survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors: A meta-analysis

•Combination regimen provides superior efficacy than immune checkpoint inhibitor monotherapy.•As an early surrogate, DCR is significantly correlated with PFS and OS.•The correlation between PFS and OS is more significant in combination groups. Immune checkpoint inhibitors (ICI) are increasingly used...

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Veröffentlicht in:	International immunopharmacology 2021-11, Vol.100, p.108135-108135, Article 108135
Hauptverfasser:	Xu, Huilin, Cao, Dedong, Zheng, Yongfa, Zhou, Dingjie, Chen, Xin, Lei, Jinju, Ge, Wei, Xu, Ximing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - mortality Clinical trials Correlation coefficient Correlation coefficients Disease control Disease control rate Evaluation Female Hepatocellular carcinoma Humans Immune checkpoint inhibitor Immune checkpoint inhibitors Immune Checkpoint Inhibitors - adverse effects Immune Checkpoint Inhibitors - therapeutic use Inhibitors Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - immunology Liver Neoplasms - mortality Male Meta-analysis Middle Aged Overall survival Patients Progression free survival Regression models Survival Time Factors
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