Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature

Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve pa...

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Veröffentlicht in:Brachytherapy 2021-11, Vol.20 (6), p.1180-1186
Hauptverfasser: Dinh, Tru-Khang T., Parker, Elizabeth U., Gangadhar, Kiran, Mansoori, Bahar, Dyer, Brandon A.
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container_issue 6
container_start_page 1180
container_title Brachytherapy
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creator Dinh, Tru-Khang T.
Parker, Elizabeth U.
Gangadhar, Kiran
Mansoori, Bahar
Dyer, Brandon A.
description Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve patients with either early stage (FIGO I) or metastatic disease. Herein, we report the only known case of locally advanced, node-positive cervical mesonephric carcinoma in a 55-year old woman with Mullerian duct anomaly of the uterus, obstructed hemivagina, and ipsilateral renal agenesis. To our knowledge, this would be the first case report with the concurrence of both rare entities. We review the treatment paradigm in this patient, and the literature, including radiotherapy and brachytherapy techniques.
doi_str_mv 10.1016/j.brachy.2021.08.002
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subjects Brachytherapy - methods
Carcinoma
Cervix Uteri - diagnostic imaging
Female
Humans
Kidney
Middle Aged
Mullerian Ducts
Solitary Kidney - complications
Solitary Kidney - diagnostic imaging
Vagina
title Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature
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