Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature
Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve pa...
Gespeichert in:
Veröffentlicht in: | Brachytherapy 2021-11, Vol.20 (6), p.1180-1186 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1186 |
---|---|
container_issue | 6 |
container_start_page | 1180 |
container_title | Brachytherapy |
container_volume | 20 |
creator | Dinh, Tru-Khang T. Parker, Elizabeth U. Gangadhar, Kiran Mansoori, Bahar Dyer, Brandon A. |
description | Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve patients with either early stage (FIGO I) or metastatic disease. Herein, we report the only known case of locally advanced, node-positive cervical mesonephric carcinoma in a 55-year old woman with Mullerian duct anomaly of the uterus, obstructed hemivagina, and ipsilateral renal agenesis. To our knowledge, this would be the first case report with the concurrence of both rare entities. We review the treatment paradigm in this patient, and the literature, including radiotherapy and brachytherapy techniques. |
doi_str_mv | 10.1016/j.brachy.2021.08.002 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2572927374</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1538472121004694</els_id><sourcerecordid>2572927374</sourcerecordid><originalsourceid>FETCH-LOGICAL-c362t-ea2e0ffb2ab2dab06c7e643c31bd45e62b54c1ec90b8c7c5672c75681f8df6223</originalsourceid><addsrcrecordid>eNp9kctu1DAUhi1ERUvhDRDykk2CL0mcYYFUlavUqpuytpyTk45HjhNsZ8q8HM-G02lZduPL8f-f3_ZHyDvOSs5483FXdsHA9lAKJnjJ2pIx8YKc8VbJglfV5mVe17ItKiX4KXkd445l20bKV-RUVrXgtZJn5O-18eYOR_SJTgN1ExjnDtT0e-MBezpinDzO22CBgglg_TSaVZm2SAHD3v6h1j_sIqZk_d16eL04h8EaT78skKhZTblrnBFSWMZc6OnirTMJg3E0oM9jvobHaOMnepGjIubyPIX0IA64t3j_lOvs6ktLwDfkZDAu4tvH-Zz8-vb19vJHcXXz_eflxVUBshGpQCOQDUMnTCd607EGFDaVBMm7vqqxEV1dAUfYsK4FBXWjBKi6afnQ9kMjhDwnH4595zD9XjAmPdoI6JzxOC1Ri1qJjVBSVVlaHaUQphgDDnoOdjThoDnTKzm900dyeiWnWaszuWx7_5iwdCP2_01PqLLg81GA-Z35N4KOYHGFZEP-Vt1P9vmEf4susMU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2572927374</pqid></control><display><type>article</type><title>Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Dinh, Tru-Khang T. ; Parker, Elizabeth U. ; Gangadhar, Kiran ; Mansoori, Bahar ; Dyer, Brandon A.</creator><creatorcontrib>Dinh, Tru-Khang T. ; Parker, Elizabeth U. ; Gangadhar, Kiran ; Mansoori, Bahar ; Dyer, Brandon A.</creatorcontrib><description>Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve patients with either early stage (FIGO I) or metastatic disease. Herein, we report the only known case of locally advanced, node-positive cervical mesonephric carcinoma in a 55-year old woman with Mullerian duct anomaly of the uterus, obstructed hemivagina, and ipsilateral renal agenesis. To our knowledge, this would be the first case report with the concurrence of both rare entities. We review the treatment paradigm in this patient, and the literature, including radiotherapy and brachytherapy techniques.</description><identifier>ISSN: 1538-4721</identifier><identifier>EISSN: 1873-1449</identifier><identifier>DOI: 10.1016/j.brachy.2021.08.002</identifier><identifier>PMID: 34521573</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Brachytherapy - methods ; Carcinoma ; Cervix Uteri - diagnostic imaging ; Female ; Humans ; Kidney ; Middle Aged ; Mullerian Ducts ; Solitary Kidney - complications ; Solitary Kidney - diagnostic imaging ; Vagina</subject><ispartof>Brachytherapy, 2021-11, Vol.20 (6), p.1180-1186</ispartof><rights>2021 American Brachytherapy Society</rights><rights>Copyright © 2021 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-ea2e0ffb2ab2dab06c7e643c31bd45e62b54c1ec90b8c7c5672c75681f8df6223</citedby><cites>FETCH-LOGICAL-c362t-ea2e0ffb2ab2dab06c7e643c31bd45e62b54c1ec90b8c7c5672c75681f8df6223</cites><orcidid>0000-0002-9595-045X ; 0000-0002-0349-4478 ; 0000-0003-0131-3677</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.brachy.2021.08.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34521573$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dinh, Tru-Khang T.</creatorcontrib><creatorcontrib>Parker, Elizabeth U.</creatorcontrib><creatorcontrib>Gangadhar, Kiran</creatorcontrib><creatorcontrib>Mansoori, Bahar</creatorcontrib><creatorcontrib>Dyer, Brandon A.</creatorcontrib><title>Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature</title><title>Brachytherapy</title><addtitle>Brachytherapy</addtitle><description>Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve patients with either early stage (FIGO I) or metastatic disease. Herein, we report the only known case of locally advanced, node-positive cervical mesonephric carcinoma in a 55-year old woman with Mullerian duct anomaly of the uterus, obstructed hemivagina, and ipsilateral renal agenesis. To our knowledge, this would be the first case report with the concurrence of both rare entities. We review the treatment paradigm in this patient, and the literature, including radiotherapy and brachytherapy techniques.</description><subject>Brachytherapy - methods</subject><subject>Carcinoma</subject><subject>Cervix Uteri - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney</subject><subject>Middle Aged</subject><subject>Mullerian Ducts</subject><subject>Solitary Kidney - complications</subject><subject>Solitary Kidney - diagnostic imaging</subject><subject>Vagina</subject><issn>1538-4721</issn><issn>1873-1449</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kctu1DAUhi1ERUvhDRDykk2CL0mcYYFUlavUqpuytpyTk45HjhNsZ8q8HM-G02lZduPL8f-f3_ZHyDvOSs5483FXdsHA9lAKJnjJ2pIx8YKc8VbJglfV5mVe17ItKiX4KXkd445l20bKV-RUVrXgtZJn5O-18eYOR_SJTgN1ExjnDtT0e-MBezpinDzO22CBgglg_TSaVZm2SAHD3v6h1j_sIqZk_d16eL04h8EaT78skKhZTblrnBFSWMZc6OnirTMJg3E0oM9jvobHaOMnepGjIubyPIX0IA64t3j_lOvs6ktLwDfkZDAu4tvH-Zz8-vb19vJHcXXz_eflxVUBshGpQCOQDUMnTCd607EGFDaVBMm7vqqxEV1dAUfYsK4FBXWjBKi6afnQ9kMjhDwnH4595zD9XjAmPdoI6JzxOC1Ri1qJjVBSVVlaHaUQphgDDnoOdjThoDnTKzm900dyeiWnWaszuWx7_5iwdCP2_01PqLLg81GA-Z35N4KOYHGFZEP-Vt1P9vmEf4susMU</recordid><startdate>202111</startdate><enddate>202111</enddate><creator>Dinh, Tru-Khang T.</creator><creator>Parker, Elizabeth U.</creator><creator>Gangadhar, Kiran</creator><creator>Mansoori, Bahar</creator><creator>Dyer, Brandon A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9595-045X</orcidid><orcidid>https://orcid.org/0000-0002-0349-4478</orcidid><orcidid>https://orcid.org/0000-0003-0131-3677</orcidid></search><sort><creationdate>202111</creationdate><title>Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature</title><author>Dinh, Tru-Khang T. ; Parker, Elizabeth U. ; Gangadhar, Kiran ; Mansoori, Bahar ; Dyer, Brandon A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-ea2e0ffb2ab2dab06c7e643c31bd45e62b54c1ec90b8c7c5672c75681f8df6223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Brachytherapy - methods</topic><topic>Carcinoma</topic><topic>Cervix Uteri - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney</topic><topic>Middle Aged</topic><topic>Mullerian Ducts</topic><topic>Solitary Kidney - complications</topic><topic>Solitary Kidney - diagnostic imaging</topic><topic>Vagina</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dinh, Tru-Khang T.</creatorcontrib><creatorcontrib>Parker, Elizabeth U.</creatorcontrib><creatorcontrib>Gangadhar, Kiran</creatorcontrib><creatorcontrib>Mansoori, Bahar</creatorcontrib><creatorcontrib>Dyer, Brandon A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Brachytherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dinh, Tru-Khang T.</au><au>Parker, Elizabeth U.</au><au>Gangadhar, Kiran</au><au>Mansoori, Bahar</au><au>Dyer, Brandon A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature</atitle><jtitle>Brachytherapy</jtitle><addtitle>Brachytherapy</addtitle><date>2021-11</date><risdate>2021</risdate><volume>20</volume><issue>6</issue><spage>1180</spage><epage>1186</epage><pages>1180-1186</pages><issn>1538-4721</issn><eissn>1873-1449</eissn><abstract>Cervical mesonephric adenocarcinoma is a rare histologic cervical carcinoma variant arising from remnants of the mesonephric duct. Few clinical cases have been reported in the literature, and given the low rate of occurrence, the optimal management strategy is unknown. Most reported cases involve patients with either early stage (FIGO I) or metastatic disease. Herein, we report the only known case of locally advanced, node-positive cervical mesonephric carcinoma in a 55-year old woman with Mullerian duct anomaly of the uterus, obstructed hemivagina, and ipsilateral renal agenesis. To our knowledge, this would be the first case report with the concurrence of both rare entities. We review the treatment paradigm in this patient, and the literature, including radiotherapy and brachytherapy techniques.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>34521573</pmid><doi>10.1016/j.brachy.2021.08.002</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9595-045X</orcidid><orcidid>https://orcid.org/0000-0002-0349-4478</orcidid><orcidid>https://orcid.org/0000-0003-0131-3677</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1538-4721 |
ispartof | Brachytherapy, 2021-11, Vol.20 (6), p.1180-1186 |
issn | 1538-4721 1873-1449 |
language | eng |
recordid | cdi_proquest_miscellaneous_2572927374 |
source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Brachytherapy - methods Carcinoma Cervix Uteri - diagnostic imaging Female Humans Kidney Middle Aged Mullerian Ducts Solitary Kidney - complications Solitary Kidney - diagnostic imaging Vagina |
title | Management of locally advanced mesonephric carcinoma of the cervix in the setting of Mullerian Duct anomaly spectrum and unilateral renal agenesis: A case report and review of the literature |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T00%3A15%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Management%20of%20locally%20advanced%20mesonephric%20carcinoma%20of%20the%20cervix%20in%20the%20setting%20of%20Mullerian%20Duct%20anomaly%20spectrum%20and%20unilateral%20renal%20agenesis:%20A%20case%20report%20and%20review%20of%20the%20literature&rft.jtitle=Brachytherapy&rft.au=Dinh,%20Tru-Khang%20T.&rft.date=2021-11&rft.volume=20&rft.issue=6&rft.spage=1180&rft.epage=1186&rft.pages=1180-1186&rft.issn=1538-4721&rft.eissn=1873-1449&rft_id=info:doi/10.1016/j.brachy.2021.08.002&rft_dat=%3Cproquest_cross%3E2572927374%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2572927374&rft_id=info:pmid/34521573&rft_els_id=S1538472121004694&rfr_iscdi=true |