A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells

Heat shock (HS) protein 70 (HSP70), a well-known HS-induced protein, acts as an intracellular chaperone to protect cells against stress conditions. Although HS induces HSP70 expression to confer stress resistance to cells, HS causes cell toxicity by increasing reactive oxygen species (ROS) levels. R...

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Veröffentlicht in:	Scientific reports 2021-09, Vol.11 (1), p.18175-18175, Article 18175
Hauptverfasser:	Ho, Khoi Thieu, Homma, Kohei, Takanari, Jun, Bai, Hanako, Kawahara, Manabu, Nguyen, Khang Thi Kim, Takahashi, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/80 692/308 692/53 Animals Asparagus officinalis Asparagus Plant - chemistry Cattle Cumulus Cells - cytology Cumulus Cells - metabolism DNA Damage Gene Expression Regulation - drug effects Glutathione Glutathione - metabolism Granulosa cells Heat shock proteins Heat-Shock Response - drug effects Heat-Shock Response - genetics HSF1 protein Hsp27 protein HSP70 Heat-Shock Proteins - antagonists & inhibitors HSP70 Heat-Shock Proteins - metabolism Hsp70 protein Hsp90 protein Humanities and Social Sciences multidisciplinary Multidisciplinary Sciences Oxidation-Reduction - drug effects Oxidative Stress - drug effects Oxidative Stress - genetics Pheochromocytoma cells Plant Extracts - pharmacology Plant Stems - chemistry Progesterone Progesterone - biosynthesis Reactive oxygen species Reactive Oxygen Species - metabolism Reference Standards Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Toxicity Vegetables
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