Removing the Obstacle to (−)‐Menthol Biosynthesis by Building a Microbial Cell Factory of (+)‐cis‐Isopulegone from (−)‐Limonene

Microbial synthesis of plant‐based (−)‐menthol is of great interest because of its high demand (≈30 kiloton per year) as well as unique odor and cooling characteristics. However, this remains a great challenge due to the yet unfilled gap between (−)‐limonene and (+)‐cis‐isopulegone. Herein, the firs...

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