Comparison of multiple oncotype DX® from the same patient
For women with breast cancer in whom multiple Oncotype DX® Recurrence Scores (RS) are obtained, RS concordance utilizing current NCCN recommendations has not been evaluated. Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance. Twenty‐four...
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| Veröffentlicht in: | The breast journal 2021-11, Vol.27 (11), p.828-831 |
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| container_issue | 11 |
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| container_title | The breast journal |
| container_volume | 27 |
| creator | Marumoto, Ashley D. Mohan, Srivarshini C. Angarita, Stephanie A.K. Srour, Marissa K. Norton, Vicky E. Dadmanesh, Farnaz Giuliano, Armando E. |
| description | For women with breast cancer in whom multiple Oncotype DX® Recurrence Scores (RS) are obtained, RS concordance utilizing current NCCN recommendations has not been evaluated. Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance. Twenty‐four patients were evaluated. RS concordance varied by tumor type: 100% in the same tumor, 91.7% in multiple ipsilateral tumors, 71.4% in contralateral tumors, and 66.7% in in‐breast recurrent tumors. RS concordance for multiple assays in the same patient is not high enough to omit Oncotype DX® testing for each tumor. |
| doi_str_mv | 10.1111/tbj.14288 |
| format | Article |
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Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance. Twenty‐four patients were evaluated. RS concordance varied by tumor type: 100% in the same tumor, 91.7% in multiple ipsilateral tumors, 71.4% in contralateral tumors, and 66.7% in in‐breast recurrent tumors. 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Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance. Twenty‐four patients were evaluated. RS concordance varied by tumor type: 100% in the same tumor, 91.7% in multiple ipsilateral tumors, 71.4% in contralateral tumors, and 66.7% in in‐breast recurrent tumors. RS concordance for multiple assays in the same patient is not high enough to omit Oncotype DX® testing for each tumor.</description><subject>Biomarkers, Tumor - genetics</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - genetics</subject><subject>Female</subject><subject>Gene Expression Profiling</subject><subject>Humans</subject><subject>multiple oncotype DX</subject><subject>Neoplasm Recurrence, Local - genetics</subject><subject>Prognosis</subject><subject>recurrence score</subject><subject>Tumors</subject><issn>1075-122X</issn><issn>1524-4741</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10L1OwzAUBWALgWgpDLwAisQCQ6iv7cQOG5R_VWIpUrfISW5EqiQOcSLUl-IheDJcUhiQ8HI9fDo6OoQcA70A96ZdsroAwZTaIWMImPCFFLDr_lQGPjC2HJEDa1eUUhZRsU9GXAQgQhmOyeXMVI1uC2tqz-Re1Zdd0ZTomTo13bpB72b5-eHlram87hU9qyv0Gt0VWHeHZC_XpcWj7Z2Ql7vbxezBnz_fP86u5n7KgSvfFYJQ5rkQCCkPQCV5plSiw4xriLimMgMaRIhMpBlTQmkMGWpgclMSJJ-QsyG3ac1bj7aLq8KmWJa6RtPbmAWSMQCmqKOnf-jK9G3t2jkVSSqU5Bt1Pqi0Nda2mMdNW1S6XcdA482gsRs0_h7U2ZNtYp9UmP3KnwUdmA7gvShx_X9SvLh-GiK_AIIqfW4</recordid><startdate>202111</startdate><enddate>202111</enddate><creator>Marumoto, Ashley D.</creator><creator>Mohan, Srivarshini C.</creator><creator>Angarita, Stephanie A.K.</creator><creator>Srour, Marissa K.</creator><creator>Norton, Vicky E.</creator><creator>Dadmanesh, Farnaz</creator><creator>Giuliano, Armando E.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>202111</creationdate><title>Comparison of multiple oncotype DX® from the same patient</title><author>Marumoto, Ashley D. ; Mohan, Srivarshini C. ; Angarita, Stephanie A.K. ; Srour, Marissa K. ; Norton, Vicky E. ; Dadmanesh, Farnaz ; Giuliano, Armando E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3138-152167ff44e1c3518bfd88ba6d3a193a07d1059ee24cd2848ae62ea1274514173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biomarkers, Tumor - genetics</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - genetics</topic><topic>Female</topic><topic>Gene Expression Profiling</topic><topic>Humans</topic><topic>multiple oncotype DX</topic><topic>Neoplasm Recurrence, Local - genetics</topic><topic>Prognosis</topic><topic>recurrence score</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marumoto, Ashley D.</creatorcontrib><creatorcontrib>Mohan, Srivarshini C.</creatorcontrib><creatorcontrib>Angarita, Stephanie A.K.</creatorcontrib><creatorcontrib>Srour, Marissa K.</creatorcontrib><creatorcontrib>Norton, Vicky E.</creatorcontrib><creatorcontrib>Dadmanesh, Farnaz</creatorcontrib><creatorcontrib>Giuliano, Armando E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The breast journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marumoto, Ashley D.</au><au>Mohan, Srivarshini C.</au><au>Angarita, Stephanie A.K.</au><au>Srour, Marissa K.</au><au>Norton, Vicky E.</au><au>Dadmanesh, Farnaz</au><au>Giuliano, Armando E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of multiple oncotype DX® from the same patient</atitle><jtitle>The breast journal</jtitle><addtitle>Breast J</addtitle><date>2021-11</date><risdate>2021</risdate><volume>27</volume><issue>11</issue><spage>828</spage><epage>831</epage><pages>828-831</pages><issn>1075-122X</issn><eissn>1524-4741</eissn><abstract>For women with breast cancer in whom multiple Oncotype DX® Recurrence Scores (RS) are obtained, RS concordance utilizing current NCCN recommendations has not been evaluated. Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance. Twenty‐four patients were evaluated. RS concordance varied by tumor type: 100% in the same tumor, 91.7% in multiple ipsilateral tumors, 71.4% in contralateral tumors, and 66.7% in in‐breast recurrent tumors. RS concordance for multiple assays in the same patient is not high enough to omit Oncotype DX® testing for each tumor.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>34514676</pmid><doi>10.1111/tbj.14288</doi><tpages>0</tpages></addata></record> |
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| issn | 1075-122X 1524-4741 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Biomarkers, Tumor - genetics Breast cancer Breast Neoplasms - genetics Female Gene Expression Profiling Humans multiple oncotype DX Neoplasm Recurrence, Local - genetics Prognosis recurrence score Tumors |
| title | Comparison of multiple oncotype DX® from the same patient |
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