Evaluation of the efficacy of a novel Vibrio vulnificus vaccine based on antibacterial peptide inactivation in turbot, Scophthalmus maximus

Tongue sole tissue factor pathway inhibitor 2 (TFPI-2) C-terminus derived peptide, TC38, has previously been shown to kill Vibrio vulnificus cells without lysing the cell membrane; thus, the remaining bacterial shell has potential application as an inactivated vaccine. Therefore, this study aimed to...

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Veröffentlicht in:	Fish & shellfish immunology 2021-11, Vol.118, p.197-204
Hauptverfasser:	Gu, Qin-qin, Wang, Guang-hua, Li, Ning-qiu, Hao, Dong-fang, Liu, Hong-mei, Wang, Chang-biao, Hu, Yong-hua, Zhang, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity AMP inactivation Animals Anti-Bacterial Agents Bacterial Vaccines Fish Diseases - microbiology Fish Diseases - prevention & control Flatfishes - microbiology Innate immunity Peptides RPS Vaccines, Inactivated Vibrio - immunology Vibrio Infections - prevention & control Vibrio Infections - veterinary Vibrio vulnificus
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