The effect of antiepileptic drugs on re-myelinization of axons: Phenytoin, levetiracetam, carbamazepine, and valproic acid, used following traumatic brain injury

Traumatic brain injury is a major health and socioeconomic problem and the first cause of young death worldwide. For this reason, the prevention of post-traumatic brain injury and the research of new methods for it are important today. In this study, we aimed to determine whether the use of antiepil...

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Veröffentlicht in:	Clinical neurology and neurosurgery 2021-10, Vol.209, p.106911-106911, Article 106911
Hauptverfasser:	DEMİRCİ, Harun, KUZUCU, Pelin, SEYMEN, Cemile Merve, GÜLBAHAR, Özlem, ÖZIŞIK, Pınar, EMMEZ, Hakan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Antibodies Anticonvulsants - administration & dosage Anticonvulsants - therapeutic use Antiepileptic agents Antiepileptics Axons Axons - drug effects Axons - physiology Brain Injuries, Traumatic - drug therapy Carbamazepine Carbamazepine - administration & dosage Carbamazepine - therapeutic use Drugs Edema Enzymes Etiracetam Glutathione Homogenization Levetiracetam - administration & dosage Levetiracetam - therapeutic use Malondialdehyde Neurotrauma Phenytoin Phenytoin - administration & dosage Phenytoin - therapeutic use Rats Rats, Long-Evans Remyelination - drug effects Trauma Traumatic brain injury Treatment Outcome Valproic acid Valproic Acid - administration & dosage Valproic Acid - therapeutic use Wound healing
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