Plasma idebenone monitoring in Friedreich’s ataxia patients during a long-term follow-up

Despite the growing interest and the potential benefits of idebenone as a repurposed drug for different orphan conditions, data regarding its monitoring are scarce. Our main goal was to report plasma idebenone values in a cohort of Friedreich’s ataxia (FRDA) patients during a long-term follow-up. Ta...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2021-11, Vol.143, p.112143-112143, Article 112143
Hauptverfasser:	Paredes-Fuentes, Abraham J., Cesar, Sergi, Montero, Raquel, Latre, Cristina, Genovès, Jordi, Martorell, Loreto, Cuadras, Daniel, Colom, Helena, Pineda, Mercè, del Mar O’Callaghan, Maria, Sarquella-Brugada, Georgia, Darling, Alejandra, Artuch, Rafael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antioxidants - therapeutic use Biological Variation, Individual Biological Variation, Population Child Child, Preschool Chromatography, High Pressure Liquid Compassionate Use Trials Drug Monitoring Electrochemical Techniques Female Follow-Up Studies Friedreich Ataxia - blood Friedreich Ataxia - diagnosis Friedreich Ataxia - drug therapy Friedreich’s ataxia HPLC with electrochemical detection Humans Long-term follow-up Male Plasma idebenone monitoring Predictive Value of Tests Retrospective Studies Time Factors Treatment Outcome Ubiquinone - analogs & derivatives Ubiquinone - blood Ubiquinone - therapeutic use Young Adult
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