Apaf1 nanoLuc biosensors identified lentinan as a potent synergizer of cisplatin in targeting hepatocellular carcinoma cells

Liver cancer is one of the most common malignancies that is difficult to treat due to late diagnosis and chemo-resistance. In the present study, we developed and validated a cell based split nanoLuc biosensor to monitor the Apaf1-Apaf1 interactions in response to apoptosis-inducing drugs such as cis...

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Veröffentlicht in:	Biochemical and biophysical research communications 2021-11, Vol.577, p.45-51
Hauptverfasser:	Wang, Zhixin, Qu, Kai, Zhou, Lei, Ren, Li, Ren, Bin, Meng, Fandi, Yu, Wenhao, Wang, Haijiu, Fan, Haining
Format:	Artikel
Sprache:	eng
Schlagworte:	Apaf1 Chemo-resistance Hepatocellular carcinoma Lentinan Split nanoLuc biosensors
Online-Zugang:	Volltext
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