A new α-pyrone from Arthrinium pseudosinense culture medium and its estrogenic activity in MCF-7 cells

A new α -pyrone analog, arthrifuranone A ( 1 ) was isolated from an EtOAc-extract of Arthrinium pseudosinense culture medium. The isolation workflow was guided by a Molecular Networking-based dereplication strategy. The chemical structure of the new compound was elucidated using MS and NMR spectrosc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 2021-12, Vol.74 (12), p.893-897
Hauptverfasser:	Kwon, Haeun, Nguyen, Quynh Nhu, Na, Myung Woo, Kim, Ki Hyun, Guo, Yuanqiang, Yim, Joung Han, Shim, Sang Hee, Kim, Jae-Jin, Kang, Ki Sung, Lee, Dongho
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 631/154/433 631/92/349 82/16 82/58 Absolute configuration Arthrinium Ascomycota - metabolism Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Breast cancer Breast Neoplasms - metabolism Brief Communication Cell culture Cell proliferation Cell Proliferation - drug effects Chemical equilibrium Culture Culture media Estrogen Receptor alpha - drug effects Estrogen Receptor alpha - metabolism Estrogen receptors Estrogenic activity Estrogens Estrogens - chemistry Estrogens - isolation & purification Estrogens - pharmacology Female Humans Life Sciences Magnetic Resonance Spectroscopy Mass Spectrometry MCF-7 Cells Medicinal Chemistry Microbiology Molecular structure NMR Nuclear magnetic resonance Organic Chemistry Phosphorylation Pyrones - chemistry Pyrones - isolation & purification Pyrones - pharmacology Workflow Xenoestrogens
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!