Dissecting the Role of N‑Glycan at N413 in Toll-like Receptor 3 via Molecular Dynamics Simulations

Toll-like receptor 3 (TLR3) is an endosomal receptor involved in initiating immune responses upon viral infection by directly recognizing double-stranded RNA (dsRNA). As one of the most heavily glycosylated TLR family members, the role of glycan at N413 of TLR3 in ligand recognition has been in deba...

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