Macromolecular assembly and membrane activity of antimicrobial D,L-α-Cyclic peptides

[Display omitted] •Membrane interactions of 2nd generation D,L-α-cyclic antimicrobial peptides.•A combined experimental (DSC, ATR-FTIR) and Coarse grained MD approach was used.•The peptides adopt different macromolecular arrangements upon contact membranes.•D,L-α-cyclic peptides with pending aliphat...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2021-12, Vol.208, p.112086-112086, Article 112086
Hauptverfasser:	Claro, Bárbara, Peón, Antonio, González-Freire, Eva, Goormaghtigh, Erik, Amorín, Manuel, Granja, Juan R., Garcia-Fandiño, Rebeca, Bastos, Margarida
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial peptides Coarse-grained molecular dynamics simulations D,L-α-cyclic peptides Differential scanning calorimetry Polarized ATR-FTIR Self-assembled cyclic peptide nanotubes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!