Urban RCT participants were healthier than non-participants or rural women
To investigate sociodemographic characteristics and physical and mental health indicators between participants and nonparticipants of a large-scale 2-year exercise RCT including noninvited women living in nearby rural area in Finland. From a previous OSTPRE study cohort, 914 women (aged 72–84) parti...
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| Veröffentlicht in: | Journal of clinical epidemiology 2021-12, Vol.140, p.44-55 |
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| creator | Vilpunaho, Tommi Sund, Reijo Koivumaa-Honkanen, Heli Honkanen, Risto Kröger, Heikki Rikkonen, Toni |
| description | To investigate sociodemographic characteristics and physical and mental health indicators between participants and nonparticipants of a large-scale 2-year exercise RCT including noninvited women living in nearby rural area in Finland.
From a previous OSTPRE study cohort, 914 women (aged 72–84) participated in Kuopio Fall Prevention Study in 2016–2019. The participants were compared to non-participants (n = 4,536) and noninvited OSTPRE women (n = 7,119) living outside the urban recruitment area.
Participants were younger (P< 0.001) with higher education (P< 0.001) and had more often regular hobbies (P< 0.001) and physical exercising (P< 0.001) than nonparticipants or noninvited. They reported better functional capability (P< 0.001), mental (P< 0.001) and subjective health (P< 0.001), lower number of medications (P< 0.001), less fear of falls (P< 0.001), but more frequent falls (P= 0.002) and more often musculoskeletal diseases (P= 0.006). Participants also showed better functional capacity in the clinical measurements. In register analysis, urban-rural differences in the prevalence of diseases were detected.
In population-based exercise interventions, participants are more likely to be better off in respect to physical and mental wellbeing, functional capability and sociodemographic status. Recruiting participants only from cities increases unavoidable selection bias due to urban-rural differences which should be noticed when interpreting and generalizing RCT results.
ClinicalTrials.gov identifier NCT02665169. |
| doi_str_mv | 10.1016/j.jclinepi.2021.08.032 |
| format | Article |
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From a previous OSTPRE study cohort, 914 women (aged 72–84) participated in Kuopio Fall Prevention Study in 2016–2019. The participants were compared to non-participants (n = 4,536) and noninvited OSTPRE women (n = 7,119) living outside the urban recruitment area.
Participants were younger (P< 0.001) with higher education (P< 0.001) and had more often regular hobbies (P< 0.001) and physical exercising (P< 0.001) than nonparticipants or noninvited. They reported better functional capability (P< 0.001), mental (P< 0.001) and subjective health (P< 0.001), lower number of medications (P< 0.001), less fear of falls (P< 0.001), but more frequent falls (P= 0.002) and more often musculoskeletal diseases (P= 0.006). Participants also showed better functional capacity in the clinical measurements. In register analysis, urban-rural differences in the prevalence of diseases were detected.
In population-based exercise interventions, participants are more likely to be better off in respect to physical and mental wellbeing, functional capability and sociodemographic status. Recruiting participants only from cities increases unavoidable selection bias due to urban-rural differences which should be noticed when interpreting and generalizing RCT results.
ClinicalTrials.gov identifier NCT02665169.]]></description><identifier>ISSN: 0895-4356</identifier><identifier>EISSN: 1878-5921</identifier><identifier>DOI: 10.1016/j.jclinepi.2021.08.032</identifier><identifier>PMID: 34487834</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Accidental falls ; Accidental Falls - prevention & control ; Aged ; Aged, 80 and over ; Angina pectoris ; Bias ; Chronic illnesses ; Clinical trial ; Disease prevention ; Education ; Educational Status ; Epidemiology ; Exercise ; Exercise Therapy ; Falls ; Female ; Fractures ; Health promotion ; Health Status ; Humans ; Intervention ; Mental health ; Musculoskeletal diseases ; Older people ; Osteoporosis ; Participation ; Patient participation ; Patient Selection ; Preventive medicine ; Questionnaires ; Research Subjects - statistics & numerical data ; Rural areas ; Rural Population - statistics & numerical data ; Selection Bias ; Socioeconomic Factors ; Urban Population - statistics & numerical data ; Wellness programs ; Women ; Womens health</subject><ispartof>Journal of clinical epidemiology, 2021-12, Vol.140, p.44-55</ispartof><rights>2021</rights><rights>Copyright © 2021. Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Dec 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-6a6c56975ac7df489dd84de83938f76aa1e01d8ecbbfa9bf305ff0d912e7fda73</citedby><cites>FETCH-LOGICAL-c444t-6a6c56975ac7df489dd84de83938f76aa1e01d8ecbbfa9bf305ff0d912e7fda73</cites><orcidid>0000-0002-5465-112X ; 0000-0002-5686-5439 ; 0000-0002-6268-8117 ; 0000-0001-5948-1222</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0895435621002791$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34487834$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vilpunaho, Tommi</creatorcontrib><creatorcontrib>Sund, Reijo</creatorcontrib><creatorcontrib>Koivumaa-Honkanen, Heli</creatorcontrib><creatorcontrib>Honkanen, Risto</creatorcontrib><creatorcontrib>Kröger, Heikki</creatorcontrib><creatorcontrib>Rikkonen, Toni</creatorcontrib><title>Urban RCT participants were healthier than non-participants or rural women</title><title>Journal of clinical epidemiology</title><addtitle>J Clin Epidemiol</addtitle><description><![CDATA[To investigate sociodemographic characteristics and physical and mental health indicators between participants and nonparticipants of a large-scale 2-year exercise RCT including noninvited women living in nearby rural area in Finland.
From a previous OSTPRE study cohort, 914 women (aged 72–84) participated in Kuopio Fall Prevention Study in 2016–2019. The participants were compared to non-participants (n = 4,536) and noninvited OSTPRE women (n = 7,119) living outside the urban recruitment area.
Participants were younger (P< 0.001) with higher education (P< 0.001) and had more often regular hobbies (P< 0.001) and physical exercising (P< 0.001) than nonparticipants or noninvited. They reported better functional capability (P< 0.001), mental (P< 0.001) and subjective health (P< 0.001), lower number of medications (P< 0.001), less fear of falls (P< 0.001), but more frequent falls (P= 0.002) and more often musculoskeletal diseases (P= 0.006). Participants also showed better functional capacity in the clinical measurements. In register analysis, urban-rural differences in the prevalence of diseases were detected.
In population-based exercise interventions, participants are more likely to be better off in respect to physical and mental wellbeing, functional capability and sociodemographic status. Recruiting participants only from cities increases unavoidable selection bias due to urban-rural differences which should be noticed when interpreting and generalizing RCT results.
ClinicalTrials.gov identifier NCT02665169.]]></description><subject>Accidental falls</subject><subject>Accidental Falls - prevention & control</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angina pectoris</subject><subject>Bias</subject><subject>Chronic illnesses</subject><subject>Clinical trial</subject><subject>Disease prevention</subject><subject>Education</subject><subject>Educational Status</subject><subject>Epidemiology</subject><subject>Exercise</subject><subject>Exercise Therapy</subject><subject>Falls</subject><subject>Female</subject><subject>Fractures</subject><subject>Health promotion</subject><subject>Health Status</subject><subject>Humans</subject><subject>Intervention</subject><subject>Mental health</subject><subject>Musculoskeletal diseases</subject><subject>Older people</subject><subject>Osteoporosis</subject><subject>Participation</subject><subject>Patient participation</subject><subject>Patient Selection</subject><subject>Preventive medicine</subject><subject>Questionnaires</subject><subject>Research Subjects - statistics & numerical data</subject><subject>Rural areas</subject><subject>Rural Population - statistics & numerical data</subject><subject>Selection Bias</subject><subject>Socioeconomic Factors</subject><subject>Urban Population - statistics & numerical data</subject><subject>Wellness programs</subject><subject>Women</subject><subject>Womens health</subject><issn>0895-4356</issn><issn>1878-5921</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0E1r3DAQgGFRUppN2r8QDL30YleS9eVbw9I2LYFCSc5ClkasjFd2JTtL_321bBJILznp8syMeBG6IrghmIjPQzPYMUSYQ0MxJQ1WDW7pG7QhSqqad5ScoQ1WHa9Zy8U5ush5wJhILPk7dN4yVljLNujnfepNrH5v76rZpCXYMJu45OoACaodmHHZBUjVsisoTrF-gaZUpTWZsTpMe4jv0VtvxgwfHt9LdP_t6932pr799f3H9vq2toyxpRZGWC46yY2VzjPVOaeYA9V2rfJSGEMAE6fA9r03Xe9bzL3HriMUpHdGtpfo02nvnKY_K-RF70O2MI4mwrRmTbnEhFDeHenH_-gwrSmW32kqCMWECo6LEidl05RzAq_nFPYm_dUE62NtPein2vpYW2OlS-0yePW4fu334J7HnvIW8OUEoPR4KCF1tgGiBRcS2EW7Kbx24x91GpR8</recordid><startdate>202112</startdate><enddate>202112</enddate><creator>Vilpunaho, Tommi</creator><creator>Sund, Reijo</creator><creator>Koivumaa-Honkanen, Heli</creator><creator>Honkanen, Risto</creator><creator>Kröger, Heikki</creator><creator>Rikkonen, Toni</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7RV</scope><scope>7T2</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5465-112X</orcidid><orcidid>https://orcid.org/0000-0002-5686-5439</orcidid><orcidid>https://orcid.org/0000-0002-6268-8117</orcidid><orcidid>https://orcid.org/0000-0001-5948-1222</orcidid></search><sort><creationdate>202112</creationdate><title>Urban RCT participants were healthier than non-participants or rural women</title><author>Vilpunaho, Tommi ; Sund, Reijo ; Koivumaa-Honkanen, Heli ; Honkanen, Risto ; Kröger, Heikki ; Rikkonen, Toni</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-6a6c56975ac7df489dd84de83938f76aa1e01d8ecbbfa9bf305ff0d912e7fda73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Accidental falls</topic><topic>Accidental Falls - prevention & control</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angina pectoris</topic><topic>Bias</topic><topic>Chronic illnesses</topic><topic>Clinical trial</topic><topic>Disease prevention</topic><topic>Education</topic><topic>Educational Status</topic><topic>Epidemiology</topic><topic>Exercise</topic><topic>Exercise Therapy</topic><topic>Falls</topic><topic>Female</topic><topic>Fractures</topic><topic>Health promotion</topic><topic>Health Status</topic><topic>Humans</topic><topic>Intervention</topic><topic>Mental health</topic><topic>Musculoskeletal diseases</topic><topic>Older people</topic><topic>Osteoporosis</topic><topic>Participation</topic><topic>Patient participation</topic><topic>Patient Selection</topic><topic>Preventive medicine</topic><topic>Questionnaires</topic><topic>Research Subjects - statistics & numerical data</topic><topic>Rural areas</topic><topic>Rural Population - statistics & numerical data</topic><topic>Selection Bias</topic><topic>Socioeconomic Factors</topic><topic>Urban Population - 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Academic</collection><jtitle>Journal of clinical epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vilpunaho, Tommi</au><au>Sund, Reijo</au><au>Koivumaa-Honkanen, Heli</au><au>Honkanen, Risto</au><au>Kröger, Heikki</au><au>Rikkonen, Toni</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urban RCT participants were healthier than non-participants or rural women</atitle><jtitle>Journal of clinical epidemiology</jtitle><addtitle>J Clin Epidemiol</addtitle><date>2021-12</date><risdate>2021</risdate><volume>140</volume><spage>44</spage><epage>55</epage><pages>44-55</pages><issn>0895-4356</issn><eissn>1878-5921</eissn><abstract><![CDATA[To investigate sociodemographic characteristics and physical and mental health indicators between participants and nonparticipants of a large-scale 2-year exercise RCT including noninvited women living in nearby rural area in Finland.
From a previous OSTPRE study cohort, 914 women (aged 72–84) participated in Kuopio Fall Prevention Study in 2016–2019. The participants were compared to non-participants (n = 4,536) and noninvited OSTPRE women (n = 7,119) living outside the urban recruitment area.
Participants were younger (P< 0.001) with higher education (P< 0.001) and had more often regular hobbies (P< 0.001) and physical exercising (P< 0.001) than nonparticipants or noninvited. They reported better functional capability (P< 0.001), mental (P< 0.001) and subjective health (P< 0.001), lower number of medications (P< 0.001), less fear of falls (P< 0.001), but more frequent falls (P= 0.002) and more often musculoskeletal diseases (P= 0.006). Participants also showed better functional capacity in the clinical measurements. In register analysis, urban-rural differences in the prevalence of diseases were detected.
In population-based exercise interventions, participants are more likely to be better off in respect to physical and mental wellbeing, functional capability and sociodemographic status. Recruiting participants only from cities increases unavoidable selection bias due to urban-rural differences which should be noticed when interpreting and generalizing RCT results.
ClinicalTrials.gov identifier NCT02665169.]]></abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>34487834</pmid><doi>10.1016/j.jclinepi.2021.08.032</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-5465-112X</orcidid><orcidid>https://orcid.org/0000-0002-5686-5439</orcidid><orcidid>https://orcid.org/0000-0002-6268-8117</orcidid><orcidid>https://orcid.org/0000-0001-5948-1222</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of clinical epidemiology, 2021-12, Vol.140, p.44-55 |
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| language | eng |
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| subjects | Accidental falls Accidental Falls - prevention & control Aged Aged, 80 and over Angina pectoris Bias Chronic illnesses Clinical trial Disease prevention Education Educational Status Epidemiology Exercise Exercise Therapy Falls Female Fractures Health promotion Health Status Humans Intervention Mental health Musculoskeletal diseases Older people Osteoporosis Participation Patient participation Patient Selection Preventive medicine Questionnaires Research Subjects - statistics & numerical data Rural areas Rural Population - statistics & numerical data Selection Bias Socioeconomic Factors Urban Population - statistics & numerical data Wellness programs Women Womens health |
| title | Urban RCT participants were healthier than non-participants or rural women |
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