Biomimetic Chip Enhanced Time-Gated Luminescent CRISPR-Cas12a Biosensors under Functional DNA Regulation

Despite that the currently discovered CRISPR-Cas12a system is beneficial for improving the detection accuracy and design flexibility of luminescent biosensors, there are still challenges to extend target species and strengthen adaptability in complicated biological media. To conquer these obstacles,...

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Veröffentlicht in:	Analytical chemistry (Washington) 2021-09, Vol.93 (37), p.12514-12523
Hauptverfasser:	Li, Cheng-Yu, Zheng, Bei, Lu, Li-Li, Fang, Wen-Kai, Zheng, Ming-Qiu, Gao, Jia-Ling, Yuheng, Liu, Pang, Dai-Wen, Tang, Hong-Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptability Analytical chemistry Antigens Aptamers Biomimetics Biosensors Blood plasma Carcinoembryonic antigen CRISPR Crystals Deoxyribonucleic acid DNA Energy transfer Interference Luminescence Metal ions Nanophosphors Nucleic acids Photonic crystals
Online-Zugang:	Volltext
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