Factors influencing the survival prognosis in older adults
Aim: The present study examined the predictive factors for the survival prognosis in older adults.Methods: The subjects were 431 patients (75-99 years old) who visited our hospital between April 2016 and March 2019. Multivariate analyses were conducted to clarify the survival prognosis (P medium >...
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| Veröffentlicht in: | Nihon Rōnen Igakkai zasshi 2021/07/25, Vol.58(3), pp.424-435 |
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| container_title | Nihon Rōnen Igakkai zasshi |
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| creator | Otsubo, Hisanori Suda, Tsuyoshi Ota, Yuri Kaji, Honami Ota, Kazuhiro Koshizaki, Masako |
| description | Aim: The present study examined the predictive factors for the survival prognosis in older adults.Methods: The subjects were 431 patients (75-99 years old) who visited our hospital between April 2016 and March 2019. Multivariate analyses were conducted to clarify the survival prognosis (P medium >high-very high, body mass index of >20.7 kg/m2, m-CONUT of normal-light >moderate-severe and sitting at discharge, and those for the 2-year survival were sitting at discharge, a SATI of >43.9 cm2m-2, a CCI of low-medium >high-very high, male moderate-severe.Conclusions: High SATI and body mass index values appeared to be associated with better survival outcomes. |
| doi_str_mv | 10.3143/geriatrics.58.424 |
| format | Article |
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Multivariate analyses were conducted to clarify the survival prognosis (P <0.05).Results: In a Cox regression analysis, the significant factors for the survival were the age (hazard ratio [HR] 1.050, 95% confidence interval [CI] 1.014-1.087), Charlson comorbidity index (CCI) (low vs. medium: HR 0.106, 95% CI 0.032-0.353; low vs. high: HR 0.244, 95% CI 0.150-0.398; low vs. very high: HR 0.514, 95% CI 0.326-0.809), pre-hospitalized gait (HR 1.861, 95% CI 1.158-2.988), sitting at discharge (HR 0.429, 95% CI 0.277-0.663), subcutaneous adipose tissue index (SATI) (HR 0.988, 95% CI 0.979-0.997) and modified controlling nutritional status (m-CONUT) (normal vs. light: HR 0.114, 95% CI 0.042-0.311; normal vs. moderate: HR 0.235, 95% CI 0.110-0.502; normal vs. severe: HR 0.351, 95% CI 0.166-0.741). In decision tree analyses, the significant factors for the 1-year survival were a CCI of low >medium >high-very high, body mass index of >20.7 kg/m2, m-CONUT of normal-light >moderate-severe and sitting at discharge, and those for the 2-year survival were sitting at discharge, a SATI of >43.9 cm2m-2, a CCI of low-medium >high-very high, male <female and m-CONUT of normal-light >moderate-severe.Conclusions: High SATI and body mass index values appeared to be associated with better survival outcomes.</description><identifier>ISSN: 0300-9173</identifier><identifier>DOI: 10.3143/geriatrics.58.424</identifier><language>jpn</language><publisher>The Japan Geriatrics Society</publisher><subject>Activities of daily living ; Adipose ; Body mass index ; Older adult ; Survival Prognosis</subject><ispartof>Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2021/07/25, Vol.58(3), pp.424-435</ispartof><rights>2021 The Japan Geriatrics Society</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c209t-c8dd7fb218abdef79c1e3a81183271c8b8b20d0778cab449c99e4bcf0e502d933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids></links><search><creatorcontrib>Otsubo, Hisanori</creatorcontrib><creatorcontrib>Suda, Tsuyoshi</creatorcontrib><creatorcontrib>Ota, Yuri</creatorcontrib><creatorcontrib>Kaji, Honami</creatorcontrib><creatorcontrib>Ota, Kazuhiro</creatorcontrib><creatorcontrib>Koshizaki, Masako</creatorcontrib><title>Factors influencing the survival prognosis in older adults</title><title>Nihon Rōnen Igakkai zasshi</title><addtitle>Nippon Ronen Igakkai Zasshi</addtitle><description>Aim: The present study examined the predictive factors for the survival prognosis in older adults.Methods: The subjects were 431 patients (75-99 years old) who visited our hospital between April 2016 and March 2019. Multivariate analyses were conducted to clarify the survival prognosis (P <0.05).Results: In a Cox regression analysis, the significant factors for the survival were the age (hazard ratio [HR] 1.050, 95% confidence interval [CI] 1.014-1.087), Charlson comorbidity index (CCI) (low vs. medium: HR 0.106, 95% CI 0.032-0.353; low vs. high: HR 0.244, 95% CI 0.150-0.398; low vs. very high: HR 0.514, 95% CI 0.326-0.809), pre-hospitalized gait (HR 1.861, 95% CI 1.158-2.988), sitting at discharge (HR 0.429, 95% CI 0.277-0.663), subcutaneous adipose tissue index (SATI) (HR 0.988, 95% CI 0.979-0.997) and modified controlling nutritional status (m-CONUT) (normal vs. light: HR 0.114, 95% CI 0.042-0.311; normal vs. moderate: HR 0.235, 95% CI 0.110-0.502; normal vs. severe: HR 0.351, 95% CI 0.166-0.741). In decision tree analyses, the significant factors for the 1-year survival were a CCI of low >medium >high-very high, body mass index of >20.7 kg/m2, m-CONUT of normal-light >moderate-severe and sitting at discharge, and those for the 2-year survival were sitting at discharge, a SATI of >43.9 cm2m-2, a CCI of low-medium >high-very high, male <female and m-CONUT of normal-light >moderate-severe.Conclusions: High SATI and body mass index values appeared to be associated with better survival outcomes.</description><subject>Activities of daily living</subject><subject>Adipose</subject><subject>Body mass index</subject><subject>Older adult</subject><subject>Survival Prognosis</subject><issn>0300-9173</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpdkD1PwzAQQD2ARCn8ALaMLCn-iGubDVW0ICGxwGw59iV15SbFdirx70kVVCSWu-W90-khdEfwgpGKPbQQvcnR27TgclHR6gLNMMO4VESwK3Sd0g5jzqslnaHHtbG5j6nwXRMG6Kzv2iJvoUhDPPqjCcUh9m3XJ39Cij44iIVxQ8jpBl02JiS4_d1z9Ll-_li9lG_vm9fV01tpKVa5tNI50dSUSFM7aISyBJiRhEhGBbGyljXFDgshramrSlmloKptg4Fj6hRjc3Q_3R0_-RogZb33yUIIpoN-SJrypVoSoRgfUTKhNvYpRWj0Ifq9id-aYH1qo__aaC712GZ0NpOzS9m0cDZMzN4G-Gew05jMM2G3Jmro2A86dnex</recordid><startdate>20210725</startdate><enddate>20210725</enddate><creator>Otsubo, Hisanori</creator><creator>Suda, Tsuyoshi</creator><creator>Ota, Yuri</creator><creator>Kaji, Honami</creator><creator>Ota, Kazuhiro</creator><creator>Koshizaki, Masako</creator><general>The Japan Geriatrics Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20210725</creationdate><title>Factors influencing the survival prognosis in older adults</title><author>Otsubo, Hisanori ; Suda, Tsuyoshi ; Ota, Yuri ; Kaji, Honami ; Ota, Kazuhiro ; Koshizaki, Masako</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c209t-c8dd7fb218abdef79c1e3a81183271c8b8b20d0778cab449c99e4bcf0e502d933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>2021</creationdate><topic>Activities of daily living</topic><topic>Adipose</topic><topic>Body mass index</topic><topic>Older adult</topic><topic>Survival Prognosis</topic><toplevel>online_resources</toplevel><creatorcontrib>Otsubo, Hisanori</creatorcontrib><creatorcontrib>Suda, Tsuyoshi</creatorcontrib><creatorcontrib>Ota, Yuri</creatorcontrib><creatorcontrib>Kaji, Honami</creatorcontrib><creatorcontrib>Ota, Kazuhiro</creatorcontrib><creatorcontrib>Koshizaki, Masako</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nihon Rōnen Igakkai zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Otsubo, Hisanori</au><au>Suda, Tsuyoshi</au><au>Ota, Yuri</au><au>Kaji, Honami</au><au>Ota, Kazuhiro</au><au>Koshizaki, Masako</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors influencing the survival prognosis in older adults</atitle><jtitle>Nihon Rōnen Igakkai zasshi</jtitle><addtitle>Nippon Ronen Igakkai Zasshi</addtitle><date>2021-07-25</date><risdate>2021</risdate><volume>58</volume><issue>3</issue><spage>424</spage><epage>435</epage><pages>424-435</pages><artnum>58.424</artnum><issn>0300-9173</issn><abstract>Aim: The present study examined the predictive factors for the survival prognosis in older adults.Methods: The subjects were 431 patients (75-99 years old) who visited our hospital between April 2016 and March 2019. Multivariate analyses were conducted to clarify the survival prognosis (P <0.05).Results: In a Cox regression analysis, the significant factors for the survival were the age (hazard ratio [HR] 1.050, 95% confidence interval [CI] 1.014-1.087), Charlson comorbidity index (CCI) (low vs. medium: HR 0.106, 95% CI 0.032-0.353; low vs. high: HR 0.244, 95% CI 0.150-0.398; low vs. very high: HR 0.514, 95% CI 0.326-0.809), pre-hospitalized gait (HR 1.861, 95% CI 1.158-2.988), sitting at discharge (HR 0.429, 95% CI 0.277-0.663), subcutaneous adipose tissue index (SATI) (HR 0.988, 95% CI 0.979-0.997) and modified controlling nutritional status (m-CONUT) (normal vs. light: HR 0.114, 95% CI 0.042-0.311; normal vs. moderate: HR 0.235, 95% CI 0.110-0.502; normal vs. severe: HR 0.351, 95% CI 0.166-0.741). In decision tree analyses, the significant factors for the 1-year survival were a CCI of low >medium >high-very high, body mass index of >20.7 kg/m2, m-CONUT of normal-light >moderate-severe and sitting at discharge, and those for the 2-year survival were sitting at discharge, a SATI of >43.9 cm2m-2, a CCI of low-medium >high-very high, male <female and m-CONUT of normal-light >moderate-severe.Conclusions: High SATI and body mass index values appeared to be associated with better survival outcomes.</abstract><pub>The Japan Geriatrics Society</pub><doi>10.3143/geriatrics.58.424</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Activities of daily living Adipose Body mass index Older adult Survival Prognosis |
| title | Factors influencing the survival prognosis in older adults |
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