Ruthenium(II) Diphosphine Complexes with Mercapto Ligands That Inhibit Topoisomerase IB and Suppress Tumor Growth In Vivo

Ruthenium­(II) complexes (Ru1–Ru5), with the general formula [Ru­(N-S)­(dppe)2]­PF6, bearing two 1,2-bis(diphenylphosphino)­ethane (dppe) ligands and a series of mercapto ligands (N-S), have been developed. The combination of these ligands in the complexes endowed hydrophobic species with high cytot...

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Veröffentlicht in:	Inorganic chemistry 2021-09, Vol.60 (18), p.14174-14189
Hauptverfasser:	da Silva, Monize M, Ribeiro, Gabriel H, de Camargo, Mariana S, Ferreira, Antônio G, Ribeiro, Leandro, Barbosa, Marília I. F, Deflon, Victor M, Castelli, Silvia, Desideri, Alessandro, Corrêa, Rodrigo S, Ribeiro, Arthur B, Nicolella, Heloiza D, Ozelin, Saulo D, Tavares, Denise C, Batista, Alzir A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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