Microneedle-mediated vascular endothelial growth factor delivery promotes angiogenesis and functional recovery after stroke

Ischemic stroke is still the major cause of disability worldwide. Although vascular endothelial growth factor (VEGF) is able to promote both angiogenesis and functional recovery, its use is limited by needle-induced injury, nonhomogenous VEGF distribution, and limited VEGF retention in the brain aft...

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Veröffentlicht in:	Journal of controlled release 2021-10, Vol.338, p.610-622
Hauptverfasser:	Liu, Yang, Long, Linyu, Zhang, Fanjun, Hu, Xuefeng, Zhang, Jieyu, Hu, Cheng, Wang, Yunbing, Xu, Jianguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Microneedle Neurogenesis Stroke Vascular endothelial growth factor
Online-Zugang:	Volltext
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