Amphotericin B nanohydrogel ocular formulation using alkyl glyceryl hyaluronic acid: Formulation, characterization, and in vitro evaluation

[Display omitted] The present study focused on the development of an amphotericin B (AmB) nanoformulation for ophthalmic applications. Accordingly, AmB nanohydrogels (AHA/AmB) using alkyl glyceryl hyaluronic acid (Hyalorepair®, AHA), a hydrophobized hyaluronic acid, were prepared by employing the di...

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Veröffentlicht in:	International journal of pharmaceutics 2021-12, Vol.610, p.121061-121061, Article 121061
Hauptverfasser:	Banshoya, Kengo, Fujita, Chiaki, Hokimoto, Yuka, Ohnishi, Masatoshi, Inoue, Atsuko, Tanaka, Tetsuro, Kaneo, Yoshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B Amphotericin B - toxicity Antifungal Agents - toxicity Fungal keratitis Fungi Hyaluronic Acid Hydrophobic and Hydrophilic Interactions Hydrophobized polysaccharide Life Sciences & Biomedicine Nanohydrogel Ocular formulation Pharmacology & Pharmacy Science & Technology
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